Ciapin1 (NM_134141) Mouse Untagged Clone

CAT#: MC204059

Ciapin1 (untagged) - Mouse cytokine induced apoptosis inhibitor 1 (Ciapin1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ciapin1
• Synonyms: 2810413N20Rik; AA617265; anamorsin; AU021794
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC021864
  GCGGAGCGGGTTTTCAGGCTACGAGGAAGTACCATTTAGGTCCAGCAGCGCGGCAGGAATGGAGGAGTTT GGGATCTCCCCTGGCCAGCTTGTGGCAGTGTTCTGGGACAAGTCATCTCCTGAGGAAGCCCTAAAAAAGC TGGTGGCTAGACTGCAAGAGTTAACTGGCAGCGAGGGCCAGGTATTCATGGAAAACGTCACCCAGCTGTT GCAGTCTTCGCATAAGGAATCCAGCTTCGATGTCATTCTGTCGGGTGTAGTCCCAGGAAGCACCTCTCTG CACAGTGCTGAGGTTCTGGCTGAGATGGCCCGGATCCTCCGGCCAGGGGGCTGTCTTTTTCTGAAAGAAC CAGTGGAGACAGCTGAAGTTAACAATGACAAAATGAAGACGGCCTCTAAGCTATGTTCAGCCCTGACTCT TTCTGGCCTCGTGGAAATAAAAGAGTTGCAGAGGGAGGCCTTAAGCCCTGAGGAGGTACAGTCCGTGCAG GAGCACCTGGGCTACCACAGTGACAGCCTGCGCTCAGTCCGTGTCACTGGCAAGAAGCCAAACTTTGAAG TGGGTTCTTCTAGCCAGCTAAAGCTTCCCAACAAGAAGTCTTCTTCAGTGAAGCCTGTTGTGGATCCTGC TGCTGCCAAGCTCTGGACCCTCTCAGCAAATGACATGGAGGATGACAGTGTGGATCTCATTGACTCAGAC GAGCTGCTTGATCCAGAGGATTTGAAGAGGCCTGACCCAGCCTCCCTGAAGGCTCCTTCATGTGGGGAAG GGAAAAAGAGGAAGGCCTGTAAGAACTGCACCTGTGGCCTCGCAGAGGAACTGGAGCGGGAGCAGTCCAA GGCGCAGAGCTCTCAGCCCAAGTCAGCCTGTGGAAATTGCTACCTGGGTGACGCTTTCCGCTGTGCCAAC TGCCCCTACCTCGGGATGCCAGCCTTCAAGCCTGGCGAGCAGGTGCTCCTGAGCAATAGCAATCTCCAGG ATGCCTAGGAGGGACCTCAAGCCCACACACCTCCTCCTCCAGCAACTCCTGTCCTCAGCTCCTCCCACGG CCTCCTCCCACCTCTGGTTTCAGGCGCTCTGAAAACACTCACAGGGAGAGGCTTGCAGCCGAGCGAGCGA GCGAAGCTGCTGTGGGCAGTGGGGTGGGGTGCTGCTGTGTCTTGAAAGACCAAGGATTGAGGGGACCTGT CTCTTAGTGTTAGGGGAAGAGGGTGGATGCGCCTAAGGAACTCTGCTCCTGGTGTTACAGTGCTGTCCCT CTCTACCCTTGAGTATTTATGCTGAGTAAGCTCCAGGCTCCGCTCAGTGATGCTGCCACCTGCTGGACTT CCTCAGGATGTAGTTCTTGGAGCCATGGGTTAGCTGTCAAAGGGCCTCAGGGGCACCAAAGAAGTCACTC CCCCAGTTGTGATCCATCTTGTGTCCCTCTGCCTTTCTCACCTCACCCCGTTTTACTGTAGTGTTGTATC TGTGTCCTGTTGTCATTTCTGTTAAATGGTATTAAACTTTTGTGTTTTTATGTCTCCCTTTAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_134141
• Insert Size: 930 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC021864, AAH21864
• RefSeq Size: 1546 bp
• RefSeq ORF: 930 bp
• Locus ID: 109006
• UniProt ID: Q8WTY4
• Cytogenetics: 8 C5
• Gene Summary: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (PubMed:14970183).[UniProtKB/Swiss-Prot Function]