Mllt10 (NM_010804) Mouse Untagged Clone

CAT#: MC203446

Mllt10 (untagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 10 (Mllt10), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mllt10
• Synonyms: Af10; B130021D15Rik; D630001B22Rik; mKIAA4140
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC070475
  TGGAATATAAGCTCTCCCGACGTTCCTAGTTACTTTCAAGGTGGATTGTGTATTTTAAGGCTGATGGGAG CGTCTGGTTTTTGGAGGAAAAAGAAGAGAAGATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAG GTCTCCCATAGTATGAAGGAAATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCTGGGCCGAGA ACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGTGCATCAAGCTTGCTATGGCATTGTTCA AGTACCTACTGGACCGTGGTTTTGTAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTGAGATGTGAG CTGTGTCCCCATAAAGATGGAGCTTTAAAAAGAACAGATAATGGGGGTTGGGCTCATGTGGTTTGTGCCC TCTATATTCCAGAGGTACAATTTGCCAATGTTTCTACAATGGAGCCAATCGTTTTACAGTCTGTCCCACA TGATCGTTATAATAAGACTTGCTATATATGTGATGAACAAGGACGAGAAAGCAAAGCAGCCACTGGTGCT TGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATGTGCTCAGTTTGCTGGGCTGC TTTGTGAAGAAGAAGGGAATGGCGCAGACAATGTTCAATACTGTGGCTACTGTAAATACCACTTTAGTAA GCTGAAAAAGAGCAAACGGGGATCTAATAGGTCATATGAGCAAAGTTTAAGTGACTCTTCCTCTCACTCT CAGGATAAGCATCATGAGAAAGAGAAAAAAAAATATAAAGAAAAGGACAAACACAAACAAAAACACAAGA AGCAACCAGAACCGTCACCTGCCTTGGTTCCTTCTTTGACTGTTACTACAGAAAAAACTTATACAAGCAC TAGCAACAACTCCATATCTGGATCATTGAAGCGCTTGGAAGATACTGCAGCAAGATTTACAAATGCAAAT TTCCAGGAAGTCTCTGCCCATACCTCTAGTGGAAAAGATGTTTCAGAGGCTAGAGGGTCAGAGGGCAAAG GGAAGAAATCTTCAGCTCACAGCTCAGGTCAAAGGGGAAGGAAGCCTGGTGCAGGAAGAAATCCAGGAAC AGCTGTGTCAGCATCTAGCCCCTTTCCACAAGGCAGTTTTTCAGGAACTCCAGGCAGTGTAAAGTCATCT TCTGGAAGTTCAGTGCAGTCTCCCCAGGACTTCTTAAGCTTTACAGACTCAGATCTGCGAAGTGACAGTT ACACTCACACCCAGCAGCCATCATCAACCAAAGATGTACATAAAGGAGAGTCTGGAAGCCAGGAAGCGGC AGTAAACAGTTTTAGCTCTTTAGTTGGTCACCCTGTGACCTCGACTGTTATTTCACAGCCTAAAAGCTTT GACAATTCACCTGGAGAGTTGGGTAGTTCGAGCCTCCCTACAGCAGGATATAAGCGGGCTCAGACTTCTG GTATAGAAGAAGAAGCTGTAAAGGAAAAGAAACGAAAAGGAAATAAGCAAAGCAAACATGGCCCCGGCCG ACCCAAAGGAAACAAAAATCAAGAAAATGTTTCTCACCTCTCAGTTTCTTCTGCTTCACCAACATCGTCC GTAGCATCAGCTGCAGGAAGTGTAACAAGCTCTAGTCTTCAGAAATCTCCTACGCTGCTCAGGAATGGAA GTTTGCAGAGTCTTAGTGTTGGCTCGTCTCCAGTTGGCTCAGAAATTTCCATGCAGTATCGACATGATGG AGCTTGTCCAACAACTACCTTCTCAGAGTTGCTGAATGCAATACACAATGGTATTTATAACAGCAATGAT GTAGCCGTATCCTTTCCAAACGTGGTGTCTGGCTCAGGATCTAGTACTCCTGTCTCTAGCTCTCATATAC CTCAGCAGTCATCTGGTCATTTGCAACAGGTGGGAGCTCTCTCCCCCTCAGCTGCGTCATCTGTAACCCC TGCTGCTGCTACAACTCAGGCAAATACCGTTTCTGGATCTTCTCTCAGTCAGGCACCAGCCCATATGTAT GGCAGTAGATTAAATCAGAATCCATCCATGGCAGTTCTCATAGCTCAGTCTGAAAGCAGCCAAACAGATC AAGATCTTGGAGACAATGCCCGTAGCCTGGGTGGCCGAGGAAGCTCGCCCCGAGGAAGCCTCTCTCCGAG ATCCCCTGTGAGCAACTTACAGCTTCGCTATGATCAACCGAGCAATAGCAGTTTGGAAACTGTGCCTCCA GTAGCAGCAAGTATTGAACAGCTCTTGGAGAGGCAGTGGAGTGAAGGACAGCAGTTTTTACTAGAGCAGG GGACTCCTGGTGACATTCTAGGAATGTTAAAGTCATTACATCAACTTCAAGTTGAAAATCGAAGATTAGA AGAACAGATCAAAAATTTGACTGCCAAGAAAGAACGTCTTCAGTTGTTGAATGCACAGCTTTCAGTGCCT TTCCCAGCCATAACGACAAACCCCAGTCCGTCCCATCAGATGCACACATACACAGCACAGACTGCTCCTC CTCCTGATTCCCTGAACAGCAGTAAGAGCCCACATATAGGAAACAGCTTTTTACCTGACAATTCTCTTCC TGTATTAAATCAGGACTTGACCTCCAGTGGACAAAGCACCAGCAGTTCTTCTGCTCTTTCTACTCCCCCT CCTGCTGGCCAGAGTCCTGCTCAGCAGAGCTCTGGAGTCAGTGGGGTTCAGCAGGTGAATGGCGTGACAG TGGGGGCACTAGCTAGTGGGATGCAGACCGTCACATCCACCATCCCAGCTGTGTCCGCAGTGGGTGGAAT AATTGGAGCTCTGCCAGGTAACCAACTGGCAATTAACGGCATTGTGGGAGCTTTAAATGGTGTGATTCAG ACTCCAGTCACAATCTCCCAGAACCCTGCCCCTCTCACCCACACCAGTGTACCACCTAATGCAGCGCATC CAATGCCGGCCGCCGCACTGACCAACAGTGCCTCGGGACTAGGGCTGCTGTCGGACCAGCAGAGACAGAT GTTTATCCAGCAGCAGCAGTTCCAGCAGCTGTTAAACTCCCAGCAGCTCACACCCGAACAGCATCAGGCC TTCCTATACCAGCTGATGCAGCAGCAGCACCACCCGCCTGAGCTCCAGCAGCTGCAGCTCCCGGGACCCA CGCAGATCCCCATCAACAATCTCCTTGCAGGTGCTCAGGCGCCTCCACTCCACACAGCTACCACCAACCC CTTCCTCACCATCCACGGGGACAGCACGAGCCAGAAGGTCACAAGACTTAGTGATAAAACTGGGCCTGTA GCTCAAGAGAAAAGTTGACACTTGAAAATGGCCAGAACTCGCCTTTCCTGCTGTTCTGTGCTTCACTGGC TGCTGCAGTGTCTGCCACAGCTATGAAGAATGGAGGCGGGAACACACAGGGGAGGATGCCACACACTCCC TTGTAAGGCTCTGATTTTCTTGTTGCTTTGTTGCACTGAAATGGAATTCCTATATACCCATCCCCTACCA AAGTGTTTGAACTTCGGAAGAAAAATTAATAACTTTTTGTCAATGAAATAATTCATATGCAATGAGTTTA TCAATCCAAGAAAAATGTAATGTGCTTGCTGCACAGCTAGTTTTGTTATAAATTGGAAACATAAAACTAA AGACTATTCTATTTGGAAACCACTTGGTTATATCATAAAAGTTGGAATATAACTATCTTATTGGGATAGA GTGTGCTTGTTCCACGGGGCAGATCTTAAGTTTTGAGAACTGTCTAATATCTTCTCTTGGAGTTGTATTC ATTAAATATTGTTATTATACAGATCCTCAACTGGGGCTTTGCAAATGTTTTAAAGAATTCCTTTCTAATG AGATTTGTCCATTTGGAGATCAAATTAGGATGGAGACAACTGCTTCTGCTAACAGTAGTTTTCTTTTGCA AAAGAAAAAAATTTTGTGTGTGTGTTAAAACCTACTCTTGAGTTAAGGGAGCTGTAAGGCTGCTGGGAGA ACTAGATCAATTGGATGAGAACAGTTTCTTTCAGAAAGATACACCAATGTGGAAACTGCTGCAAGGTTCT AGCATCAAATTGCCTGTTGGGACCTCCCTGGATAGAAAGGGCTCTGTACTGCCGGGCAGGCCACTTGTGC CAGCAGCTTCCCCGTGCTTCTGTCTCTGTTGAACCTTTCTGTGCCACCAGAGAGAGCTCAGGCAAACTGA CTGTCCACAAGGAAACAAGTAGACCTGGGAAGAGTCTACATGCTTGCTTATCTCATCAGCCTCAAACCAC CCACTGGAACAGGCACACCACCACAGTTCCTAAAACCTGTCCCACAGCCTTCCGACTTAGCCATGCCCCG AGTAGCCATGCTCTTGATTGTGACAATATGGCAGCCTAGTAGGTTAGACAGTTGGGGATATAATCATTGG TCTGTTTCTGAAACACATGAATTACTGGTGGGAAAGGCCCAACTGCAGTTCGACCTCCACTGTGTGCTTA GCTGGAAGACCATGTGCACGGCTTAGCAGTCTGTCTTCTGTGACACTGCACACCTCTTACCTCACTTCTG TAAATAAGGTTGTGAATCTGTTTTGTAATGTGAAAAATTCATAAGATAACATTGATATTTTGATTTGTAA TATTTCTAATTGGTAGATTTAATTGAAAAGTAAAATTAATTTATTTTTATATGTTCAGGGGAATTTTAAA GAAAGTCAAACCTTTTGTAGATAATTTAAAAGAATCAGTGTGGTTTATTTTATATATGTAACCCACTGGT TGTTATTCTGTAACAATTTGTATAAATGGTAAATTTTTGAATGTGCTGTTATTTTACTTAGATGTAAAAT TCCACATGTATTAAAATGTACAAAGTTTTTGTTAATAAAATTTAATGATGTTTATAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_010804
• Insert Size: 3207 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC070475, AAH70475
• RefSeq Size: 4918 bp
• RefSeq ORF: 3207 bp
• Locus ID: 17354
• UniProt ID: O54826
• Cytogenetics: 2 A3
• Gene Summary: Probably involved in transcriptional regulation. Binds to cruciform DNA (By similarity). In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).