Hps4 (NM_138646) Mouse Untagged Clone

CAT#: MC203415

Hps4 (untagged) - Mouse Hermansky-Pudlak syndrome 4 homolog (human) (Hps4), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Hps4
• Synonyms: 2010205O06Rik; AU040608; BLOC-3; C130020P05Rik; le; mKIAA1667
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC063055
  TCCACCTCCAGTCCTCCTGGACTTGTCAGCAGTGCAGAGATACTTCTGGAAAGGAACCTGCCCCGAAGGG AAGTTGCCTTTTCATATTGATTCAAGAGTGAACAAGAGGCAGAAACCACCTGGATGGTCCACACCTGGCA TCACTGAGCTGGGGACACCAGTTGGGGGACAGAGAACTGCTTCTAGGAAGAACACCAGATGAAGAGGATG AAGCCATCTGGAGAGTAAATGGCCACCACCACTCCCCCAGAGACAAAGTCAGCAGCGTGGTGGAACTACT TCTTCCTGTATGACGGTTCCAAGGTAAAGGGAGAAGGAGACCCAACCAGAGCTGGCATCTGCTACTTCTA TCCGCCCCAGACCCTGTTAGACCAGCAGGAACTGCTCTGTGGCCAGCTTGCTGGAGTAGTGCGCTGCCTG TGGGACCTTTCTGGCACCCCGCCCATGCTCATCCGTATGCGGAACCTCAAGTTTGCCATCAGGGCAGATG GGGACTACCTGTGGGCTCTGGGGTGTGGTGTGGAGATCTCTGATGCCAGCTGCAGGCAGTTTCTGGATCA GCTCATTGGATTTTTTCATTTCTACATGGGCCCTGTCTCCCTGGCCTACAAGAGCCATCCTCAGGAGGAG CTGAGCTTGCAGTGGGATACCTCCATCACACAAGTCCTCAGGAGCACCAGCGAATCGCACAGGATCTTCA ATGCCCTGTGGAACCTGGACCGCACCAAAGTGGAGCCCCTGCTGCTGCTGAAGGCAGCTCTCATCTTACA GACCTGCCAACGCTCACCTCATGTGCTAGCTGGCTGCATCCTCTATAAAGGACTGATTGTGAATTCCCAG CTCCTGCCTTCCCTCACTGCTAAGGTCCTGCTTCATCAGACTGTACCTGCAGACCAGAGGCTGCCTGGAG CAGGAGCTGCCCCACAGGAAACAGGAGCAGCGTTGCCCCCGGATGTGCAGATCACCTCTGTTTTTCTGAG TGAGGAGGAAGCTGCCAGCCTCCACGAGTTCCCAGTAGAGCATGAAACTCGACTCCAGGGAAGTTCAGTT CAATACCCTCCCTGGGATCAAAGCAGCCCCACCCAGGCAGAAGATGCCTGGGCATCAGCTGCCATCCCGG AGCCCACGCCGCATGATGGAGCATGTCCGAGTGGCAGCGGGGCAGATGAACGCTTGCCTAGGCTTGAGCA GGAGTGTGCTGGGCCCACGGGACTGTGCACCACTGCCTGTGGCCAGGGCTCCGGCCTCAGCAGCAGGCTG CAGAAGGAGCTGTGTCTCTCCCGGGAGGAACTGGACTCGTCTGAAATGCACGTTTCTGAGGCTCAGGAAG CCTTCCCACCTTTGCCTGCCCTGGGTGATCTGGAGACTCTCCACAGCAGCCACAGTGCCCCCACTCTACC TGAAGACACAGCCATTTGCAGCTGCCTGCACCCTTGCCCTCTTGAGAGGCTCCCTGAGAGTGGAAGGCTA GGACAGCTCGCAGACCTGCCCCTCACCAATGGCCAAACCCAGGTTCCTGGCACAGACCCTCTCCCCAGCA GCATGCCTGTGGCACTTCCTCCCCAGCATCCTGTGGGTGTAGAGCCCAGTGTGGAGCCATACGGGAATGG AGCCCAGGAGAGCCACTCAGCCCTGCCACGCAGTTCCCGCTCACCTGACTCTCCGGGCCCCAGCCCCTCT GCAGACAGAACTGGCTTCAAGCCATCCCCATCTGGACGCCACGCAGGGCTCGTGCCCATGAACCTCTACA CCCACAGTGTGAACGGACTGGTGCTGTCCCTGCTGGCCGAAGAGACTCTTCTCAGCGACACTGCAGCCAT CGAGGAGGTGTACCACAGCAGCCTGGCGTCGCTGAATGGGCTGGAAGTCCACCTGAAGGAGACGCTGCCC AGAGACGAGGCTAGCCTCACCAGCAGCACATACAACTTCCTTCATTATGACCGCATCCAGAGCGTGCTCT CAGCCAACCTGCCCCTAGTGACTGCTCCCCAGGACCGCCGGTTTCTGCAGGCCGTCAACCTCATGCACTC CGACTTTGCCCTGCTGCCTATGCTGTACGAGATGACCATCAGGAACGCCTCCACAGCCGTGTACGCCTGC AGCAGCCCAGCCCAGGAGACCTACTTCCAGCAGCTGGCACCCACTGCCCGCAGCTCTGGCTTCCCAAACC CTCAGGATTGCGCCTTCAGCCTCGCAGGCAAAGCCAAGCAGAAGCTGCTGAAGCACGGGGTAAACCTGCT GTGAGCTGGGTGCAGCTTGCATATCACGAGGGCCATGTCCCCAATGCTAACGGTTGAGCGGGCCCTTGCT CCTCAGTGGCAGCTGCAAGAACTGAGTGGGCTCAGGTCCTGTCCTGTGGAAGCCTTGAGGGCGGTGCAGA GCAGGCTGCAGGCTCAGGAATGCAGCGGCAGGATTCACTGCTGACCGTTTACTTGAGATACCCATGGTGC TTTGTAACCGTATGGTGCCCAGTTCCAGGTTTATGAAGCAGATTCCCAAAGGCTCAAAAATAAAATGACC AAAGTGAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_138646
• Insert Size: 2016 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC063055, AAH63055
• RefSeq Size: 2545 bp
• RefSeq ORF: 2016 bp
• Locus ID: 192232
• UniProt ID: Q99KG7
• Cytogenetics: 5 54.69 cM
• Gene Summary: Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.