Rsad2 (NM_021384) Mouse Untagged Clone

CAT#: MC203237

Rsad2 (untagged) - Mouse radical S-adenosyl methionine domain containing 2 (Rsad2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rsad2
• Synonyms: 2510004L01Rik; cig5; Vig1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC057868
  GTCACCATGGGGATGCTGGTGCCCACTGCTCTAGCTGCTCGGCTGCTGAGCCTGTTCCAGCAGCAGCTGG GTTCCCTCTGGAGTGGCCTGGCCATCCTGTTCTGCTGGCTGAGAATAGCATTAGGGTGGCTAGATCCCGG GAAGGAACAGCCACAGGTCCGGGGTGAGCTGGAGGAGACCCAGGAGACCCAGGAAGATGGGAACAGCACT CAGCGCACAACCCCCGTGAGTGTCAACTACCACTTCACTCGTCAGTGCAACTACAAATGTGGCTTCTGCT TCCACACAGCCAAGACATCCTTCGTGCTGCCCCTGGAGGAGGCCAAGCGAGGACTGCTTCTGCTCAAACA GGCTGGTTTGGAGAAGATCAACTTTTCTGGAGGAGAACCCTTCCTTCAGGACAGGGGTGAATACTTGGGC AAGCTTGTGAGATTCTGCAAGGAGGAGCTAGCCCTGCCCTCTGTGAGCATAGTGAGCAATGGCAGCCTTA TCCGGGAGAGATGGTTCAAGGACTATGGGGAGTATTTGGACATTCTTGCTATCTCCTGCGACAGCTTCGA TGAGCAGGTTAATGCTCTGATTGGCCGTGGTCAAGGAAAAAAGAACCACGTGGAAAACCTTCAAAAGCTG AGGAGGTGGTGCAGGGATTACAAGGTGGCTTTCAAGATCAACTCTGTCATTAATCGCTTCAACGTGGACG AAGACATGAATGAACACATCAAGGCCCTGAGCCCTGTGCGCTGGAAGGTTTTCCAGTGCCTCCTAATTGA GGGTGAGAACTCAGGAGAAGATGCCCTGAGGGAAGCAGAAAGATTTCTTATAAGCAATGAAGAATTTGAA ACATTCTTGGAGCGTCACAAAGAGGTGTCCTGTTTGGTGCCTGAATCTAACCAGAAGATGAAAGACTCCT ACCTTATCCTAGATGAATATATGCGCTTTCTGAACTGTACCGGTGGCCGGAAGGACCCTTCCAAGTCTAT TCTGGATGTTGGCGTGGAAGAAGCAATAAAGTTCAGTGGATTTGATGAGAAGATGTTTCTGAAGCGTGGC GGAAAGTATGTGTGGAGTAAAGCTGACCTGAAGCTGGACTGGTGAGGCTGAGATGGGAAGGAAACTCCGA CCAGCTACAGGGACATTCACGCCCAGCTATCCTTCAACAAGCTACATCTTCTGGCTGTCTACAGACTGTT GTTATTAGAACACAGTCTGTTTATTTTTCTTTCAGTTTGACTGAACTAAAAAGGGAGTAAAATTATGCAG CAGATAATCGTCCTCCACAGGAGAGAGTTCGGTTCTCAGAGGAGCAAGGTCCAGTGACCCCTAAGAACCA GCATTTCATTTATATTTGAATTTTTGTGTGGATTTTACTGTGAATCCCACATTTCCTTTTTCCTTTTTGT TCCCCTTGAGAAACTGGGTTATTTTTTGCTAACTATGCCAATTTTGTCAACAGGAAACTTCACAAAACAC ACCCTCCAATTACTGCTGACTATTCTAATGCTTTTCTGCTTTGGAATATTGGACTTTTTACTCAAAAGTG TAGAATCAAGGCATATCTCATAGAACCTTAAGTTAGAATCTTACTCTTATGGAAGGAGTTATTTCCTAGA ACAGGCTGTTTGTTCATGGTCCCAGCCTCTGATGCTGCTGCTTCAAGATGGCTGCTTTATACTGCAGCAA TTCCTTCAGGGTTCTTGACAAAGCCAAGGTACACTTTACCTCCCAGGGTGTGGCAATGAGGATGCCACTT CTGCAGCTGCAACTGCCCTGGCATTGAGGCTGCTTGAGTCTCTCATGCTGAAAGGTTGTCACACTTTTCT GAAAAGCTCAAGGCCATGTGGCACGTCCAGAAGAGTCGTGGGGGGATAGACAGGAAGGAGTCTTTCAGGA ATATAAAATGTGGCAGCTGGCTTGGTATAAATGTGCCTGTGGTTCCTTAGCATATCTTTCAAGAAACACT GAAACTTGACCTAGTCTAGGTCAACATGAGAAAAACAAAAAAAACAAAACAAAACAAAAAAAAAAAAAAA AA
• Restriction Sites: RsrII-NotI
• ACCN: NM_021384
• Insert Size: 1089 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC057868, AAH57868
• RefSeq Size: 2032 bp
• RefSeq ORF: 1089 bp
• Locus ID: 58185
• UniProt ID: Q8CBB9
• Cytogenetics: 12 A2
• Gene Summary: Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphosphate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.[UniProtKB/Swiss-Prot Function]