Sel1l (NM_011344) Mouse Untagged Clone

CAT#: MC202913

Sel1l (untagged) - Mouse sel-1 suppressor of lin-12-like (C. elegans) (Sel1l), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sel1l
• Synonyms: AW493766; mKIAA4137; Sel1h
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC026816 sequence for NM_011344
  GGAAGAGCGGCTGCGAGGCGGCGGCACAGAGGCAGCGGCTGAGTTGGTCGCGGCGACGGCGACGGCGACG GCGAGGGCTCTCGACCTTCGAGAGCAGGATGCAGGTCCGCGTCAGGCTGTCGTTGCTGCTGCTCTGCGCG GTGCTCCTGGGCTCGGCAGCCGCGACCTCGGATGACAAAACTAACCAGGATGACTCCTTAGATTCCAAGA GTTCTTTGCCCACAGATGAGTCAGTGAAGGACCACACCACCACGGGCAAAGTAGTTGCTGGCCAGATATT TGTTGATTCTGAAGAAGCAGAAGTGGAATCCCTTCTTCAGGACGAGGAAGATAGCTCCAAGACCCAGGAG GAAGAGATCAGCTTTTTAGAATCTCCGAATCCAAGCAGCAAGACCTACGAAGAACTAAAGAGAGTGCGGA AGCCAGTCTTGACTGCCATTGAAGCTGAAGAAGATGCTGCCAAAAGACGACAGATGCAGGAAGCAGAGAT GATCTATCAGGCCGGGATGAAGATACTGAATGGAAGCAATAGGAAGAGCCAAAAGAGAGAAGCATATCGG TACCTTCAGAAGGCAGCAGGCATGAATCACACCAAAGCCCTGGAGAGAGTGTCCTATGCTCTCTTGTTTG GTGATTACCTCACACAGAATATCCAGGCAGCCAAAGAGATGTTTGAGAAACTGACTGAGGAAGGGTCTCC CAAAGGACAGACTGGTCTTGGCTTTCTCTACGCTTCTGGGCTTGGTGTTAATTCAAGTCAGGCAAAGGCT CTTGTATATTATACTTTCGGAGCTCTTGGAGGCAACCTGATAGCCCATATGATTTTGGGTTACCGCTACT GGGCTGGCATCGGAGTCCTCCAGAGTTGTGAGTCGGCACTGACCCATTATCGTCTTGTTGCCAATCATGT TGCTAGTGATATCTCCCTAACTGGAGGCTCTGTAGTCCAGAGAATACGGCTGCCCGATGAAGTGGAAAAC CCGGGGATGAACAGTGGGATGCTGGAAGAAGACCTGATTCAGTATTACCAGTTCCTAGCTGAGAAGGGTG ACGTCCAAGCACAGGTTGGCCTGGGACAGCTGCATCTGCATGGAGGGCGTGGAGTAGAACAGAATCACCA GAGAGCGTTTGACTACTTCAACTTAGCAGCAAATGCTGGCAATTCACATGCTATGGCCTTCCTGGGAAAG ATGTATTCTGAAGGAAGTGACATCGTACCTCAGAGTAATGAGACGGCACTTCACTACTTTAAGAAAGCTG CTGACATGGGCAACCCCGTGGGACAGAGCGGGCTTGGAATGGCCTACCTCTACGGAAGAGGCGTTCAAGT TAATTATGACCTGGCCCTCAAGTATTTCCAGAAAGCTGCTGAGCAAGGCTGGGTGGACGGGCAGCTGCAG CTCGGCTCTATGTACTACAATGGCATTGGAGTCAAGAGAGATTATAAGCAGGCCTTGAAGTATTTTAATC TGGCTTCTCAAGGAGGCCATATCTTGGCTTTCTATAACCTCGCACAGATGCACGCCAGCGGCACAGGGGT GATGCGGTCCTGTCACACTGCAGTGGAGTTGTTTAAGAATGTGTGTGAGCGAGGTCGCTGGTCAGAGAGA CTGATGACTGCCTACAACAGCTATAAGGATGAGGACTACAATGCTGCAGTGGTCCAGTACCTCCTGCTGG CTGAGCAGGGCTACGAGGTGGCGCAGAGCAACGCAGCCTTCATCCTCGACCAGAGAGAAGCAACCATTGT AGGTGAGAATGAAACTTACCCCAGAGCTTTACTGCATTGGAACAGGGCCGCCTCCCAAGGTTACACTGTG GCTAGAATTAAGCTTGGAGACTACCACTTCTATGGCTTTGGCACTGATGTGGATTATGAGACCGCATTTA TTCATTACCGCCTGGCTTCTGAGCAGCAGCACAGCGCCCAAGCTATGTTTAACCTGGGCTACATGCACGA GAAGGGCCTAGGCATTAAACAGGACATTCACCTTGCAAAACGCTTTTATGACATGGCAGCCGAAGCTAGC CCAGATGCACAAGTACCTGTGTTCCTCGCACTCTGCAAATTAGGTGTCGTCTATTTCTTACAGTACATAC GGGAAGCAAACATTCGAGATCTATTCACACAACTGGATATGGACCAGCTTTTGGGACCCGAGTGGGACCT TTACCTCATGACCATCATTGCACTGCTCTTGGGTACAGTCATAGCTTACAGGCAGCGACAGCACCAGGAC ATACCAGTTCCCAGGCCCCCAGGGCCACGGCCGGCTCCTCCCCAGCAGGAAGGACCACCAGAGCAGCAGC CACCACAGTAGCAGCCACACACTCACCTTGGTCGGTGACCACTGGGGAGCTGCTTGCTGAGAACGCTTGC ATTTGATGTAGGGCTCTGGATGGTGGCACCGCCTGGAAGAGGCGTGAGGCGTGTTGAATCCCAGAAGCTG CTTAGAACCTGCTGCCTTCCTTTTCAGGGATGCGCGGCTCTCGGCAGAGCTGCAGTGAATGTTTGTTTCA GTGCCATACGGAATGACAACTCTCAGTGGCTTTCCTCTTTCCTTTTTCTTTCTTCGTTCTGCAAACATAC ACAAGACACTCGAGTCATGTCTACTGTACCCTGTCTTTCCTGAGAGACCTTTCGTCATCCTGTTGATGTG CATAACTTCTTACCTGTCTTCTAAGGTCCTGAGCATTGACAACCTGGGGAAACCCAGTTAGTTGCAAGTT TAACCCTAAAAACATGCTTAAGTCTGAGACTAGAACTTGCCATTAAGTCAAAAGCAAAACAAGCCAAGCA GGACGTCTTCAGGGTGTTTGGGAAATGCAGTAACTGGGAAATTTTACCAGTCTACATGCCAGGTCATATG TTCGGCACGCTTATTTTAAAAGGGATTATTGATCGGATTCCTGTACTGTGACTCTGACACTTCCTAGCAA ACTTCTCTTCCTCAAAGACTGAAAGGCTTTGCTAAAGACTTCTTCGTGATGTCACATCCCTGCCATGGAG TAGAAGTCAAACTCAGTCAGCTGACTCCGTGCTCCCACAGAGGACTTTGCCCCAGCTACTCATGTGAGTT GCATATACAGAGCCCTAGTCCAGACGCCAGAGGATGATCTAAATGGAGAAATCAGAAAACAGCCTTAACC AACTTGAGGTGGGACCTGGGACATGCCCTCCCTCGGGTAGATTCGTTGCTTCCCGGATCTCATTTTACTT CACATTTCTTATGGCACAGAGAACAGACAACCCTCCCAAAGTCTTCAAATATGAAATGCTATTGTCAAGA TTGGCAGGTGGTGACTTCCTTTGTAATACTAAAATACTAAAATACTCAGACAATGGAGGATGGGTTAGAC CCAATGCATGGCAAAACCAAAGGCCTGGGTGCACCGTTGTGTATGCTGCGGGAGCTTTTTATTTCTGACG GTTTGATGTGGCTGTAGAAAGTCAGCCACTGAGTAGCTGTTGTGTTATCGCCCTTCTGTTGTAAACATTA GGAAATTAAAGCAGTTACACCCAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_011344
• Insert Size: 2223 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC026816, AAH26816
• RefSeq Size: 3540 bp
• RefSeq ORF: 2223 bp
• Locus ID: 20338
• UniProt ID: Q9Z2G6
• Cytogenetics: 12 D3
• Gene Summary: Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:25066055, PubMed:24453213). Enhances SYVN1 stability (PubMed:24453213). Plays a role in LPL maturation and secretion (PubMed:25066055). Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells (PubMed:20170518, PubMed:24453213). May play a role in Notch signaling (PubMed:20170518).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) has an alternate splice site in the coding region, compared to variant 1. The resulting isoform (b) lacks an internal segment, compared to isoform a. Sequence Note: This sequence has been modified as follows: removed 22 bp suspected to be vector contamination from the 3' end.