Cyp2s1 (NM_028775) Mouse Untagged Clone

CAT#: MC202735

Cyp2s1 (untagged) - Mouse cytochrome P450, family 2, subfamily s, polypeptide 1 (Cyp2s1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cyp2s1
• Synonyms: 1200011C15Rik; AU041727; C79779
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC064733 sequence for NM_028775
  CGGCAAGGAGCTTCTAGGAGGTACAGACCCAGCCGACCTGCAGAGATGGAGGCAGCCAGCACCTGGGCGC TGCTGCTGGCCCTGCTGCTGCTGCTGCTGCTGCTGTCTCTGACGCTATTCAGGACCCCGGCCCGAGGCTA CCTACCCCCGGGGCCCACGCCGCTGCCGTTGCTGGGGAACCTCCTGCAGCTGCGTCCCGGGGCTCTGTAC TCGGGGCTTTTGCGGCTAAGTAAGAAGTATGGGCCTGTGTTCACGGTATACCTGGGCCCCTGGCGCCGCG TGGTGGTCCTGGTTGGACATGATGCTGTAAGAGAAGCCTTGGGAGGTCAGGCTGAGGAATTCAGCGGGCG TGGAACATTGGCAACGCTGGACAAGACCTTTGATGGTCACGGAGTTTTCTTTGCCAATGGGGAGCGGTGG AAACAGCTGAGGAAATTCACCCTGCTCGCTCTACGGGACCTGGGCATGGGCAAGCGAGAAGGCGAGGAGC TGATCCAGGCGGAGGTGCAGAGTCTGGTGGAGGCTTTCCAGAAGACAGAAGGACGTCCATTCAACCCTTC CATGCTGCTGGCCCAGGCCACCTCTAATGTCGTCTGTTCCCTTGTCTTTGGCATCCGTTTGCCCTATGAC GATAAAGAGTTCCAGGCTGTGATCCAGGCAGCAAGTGGTACCTTGTTAGGGATCAGCTCTCCATGGGGCC AGGCCTACGAGATGTTCTCCTGGCTACTGCAGCCCCTGCCAGGCCCCCACACACAGCTCCAGCACCACTT GGGCACCCTGGCTGCCTTCACTATCCAGCAGGTACAGAAACACCAGGGACGCTTCCAAACCTCAGGTCCT GCACGTGATGTCGTTGACGCCTTCCTGCTAAAGATGGCACAGGAGAAACAAGACCCAGGTACAGAATTCA CCGAGAAGAACTTGCTGATGACGGTCACATACCTGCTGTTTGCTGGGACCATGACCATCGGTGCCACCAT CCGCTATGCCCTCCTGCTCCTGCTGAGATACCCTCAAGTCCAGCAGCGCGTCCGGGAGGAGCTCATACAG GAGCTGGGTCCTGGCAGGGCTCCAAGTCTCAGCGATCGAGTTCGCCTCCCTTACACGGATGCCGTTTTAC ACGAGGCACAGCGGCTCCTGGCACTGGTACCCATGGGCATGCCCCACACCATCACGAGGACCACTTGCTT CCGAGGGTACACTCTGCCCAAGGGCACTGAGGTCTTCCCTCTGATTGGCTCCATACTGCATGACCCTGCG GTTTTCCAGAACCCAGGAGAGTTCCATCCAGGCCGCTTCCTGGACGAAGATGGTCGGTTGAGAAAACACG AAGCCTTCCTGCCCTACTCCTTAGGTAAGCGAGTCTGCCTGGGAGAAGGCCTGGCTCGGGCGGAGTTGTG GCTTTTCTTCACTTCCATCTTGCAAGCCTTCTCCCTGGAGACCCCGTGCCCGCCGGGTGACCTGAGCCTG AAGCCAGCCATCAGTGGACTTTTCAACATCCCCCCGGACTTCCAGCTGCGGGTCTGGCCCACTGGCGACC AGTCCAGATGAAGGAAGGAGTTTGGAAGGTGGGAGCCCTCTGGGCTGAAAGAGCCTTACTCAGGGTGTGT GTGAAGCAGGTGTCTCAGAAGCAACATCACACTACACACCACGTATCAAGGCAGCTGTGGAGACCAGGGA CCACACCACTACACAACCGCACAGCAACTGATGCATAGGCTTCTTTTTGGAGAGGGCTGTCTGAAACGGG GATCTTGTTATGTGGTGACACAAGCCGAACTCAAACTTGTGATCCTCCCGCCTCGGTGTCCTGCTCGCTG GAATTACAGGTATGCGCCACCATGAGCTGCATAGGCTTTCAGCCTACATCATGTAATATAGGCCATCTGG AATTGCAAGCATATAGCTAGATACCCCGCTGTCCACCACACGACTCTGTATGCTCACAACTCTAATCCAG CGACTGCCTACACAAACACACAAACAACCCAACCGTATTCAGGACTCTTAACTCTGTCTAACACGCTCAG CACCGCTGTTGCTGGGTCCCCGCCATAGAAAACAGCAAGCCCCAGCTGGGGTCATGTCACAGCCAGAACG ATGTTCTGTCTACTCCCATGGATGACCTCACCACCATCCAGGCTCATGAGTGGCTCTATCAACGGCCACC AGCCAGTAATCCACACAGCCAAACCGTATGTGACAAGATCTTGGCCCTTCCAAACTTCTTCCCACTGAGG CACACCGTGACGACATACTATTCCCCAGTCACGTCCACACCCATGCCCCTCCAGCACGCTCCTTCCAACA AATGTTCCCAAATATAAAGGTTTCCTGGTCTGTGATTGTGCACACAGACCTTCTACAAATGAGGACCAGC GACCCAAAGAAAAAGGGTTTCCCAGTCATGTTATCAGGGGCCTGCTCTCAAACGCATTCTGATCTCTGAG CTGCCTGCAAGTCCTCATGAGAGTGCTGGAAATGTATCCTCCTCCTGGAAGGACTAACTGGCCTCACAGG GATGATGCAGGGGAGTGCTGTTAGCTGTTTCCAGCCCTCCTTATCAGGACAGAAGCCATAGCTGACCTCT TTGTGACTTGAAGGTTCCCGTTTTGCAATAAAAGTTTGTTTCTGGCCCGAAAAAAAAAAAAAAAAAAAAA AAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_028775
• Insert Size: 1506 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC064733, AAH64733
• RefSeq Size: 2664 bp
• RefSeq ORF: 1506 bp
• Locus ID: 74134
• UniProt ID: Q9DBX6
• Cytogenetics: 7 A3
• Gene Summary: A cytochrome P450 monooxygenase involved in the metabolism of retinoids and eicosanoids. In epidermis, may contribute to the oxidative metabolism of all-trans-retinoic acid. For this activity, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Additionally, displays peroxidase and isomerase activities toward various oxygenated eicosanoids such as prostaglandin H2 (PGH2) and hydroperoxyeicosatetraenoates (HPETEs). Independently of cytochrome P450 reductase, NADPH, and O2, catalyzes the breakdown of PGH2 to hydroxyheptadecatrienoic acid (HHT) and malondialdehyde (MDA), which is known to act as a mediator of DNA damage.[UniProtKB/Swiss-Prot Function]