Cited2 (NM_010828) Mouse Untagged Clone

CAT#: MC202716

Cited2 (untagged) - Mouse Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Cited2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cited2
• Synonyms: AI835299; ER154-like; Mrg1; Msg2; p35srj
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC057126 sequence for NM_010828
  GCCTGGCGGTCTTGCGGAGCGGCTAGGGCAGCGGAGGAAAAGAAAAGGGAACGGCTCGGAATTTGCTCCA GCGGCTGCTGCAAGACCTCGGCGCCAACCTCGCACCGGCGAGCGCCTCACAGCCCATCGGCTGTCCCTCT ATGTGCTGCTGAGCCGGTCCTGGACTCGACGAGCCCGCCTTCGGTGTTCCGAGCAGAAATCGCAAAGACG GAAGGACTGGAAATGGCAGACCATATGATGGCCATGAACCACGGGCGCTTCCCCGACGGCACCAACGGGC TGCACCACCACCCTGCCCACCGCATGGGCATGGGGCAGTTCCCGAGCCCGCATCATCACCAGCAGCAGCA GCCCCAGCACGCCTTCAACGCCCTCATGGGCGAGCACATACACTACGGCGCGGGCAACATGAATGCCACG AGCGGCATCAGGCACGCCATGGGGCCGGGGACTGTGAACGGGGGGCACCCCCCGAGCGCTCTGGCCCCGG CCGCCAGGTTTAACAACTCCCAGTTCATGGGTCCCCCGGTGGCCAGCCAGGGAGGCTCCCTGCCGGCCAG CATGCAGCTGCAGAAGCTCAACAACCAGTATTTCAACCATCACCCCTACCCCCACAACCACTACATGCCG GATTTGCACCCCACTGCAGGCCACCAGATGAACGGGACAAACCAGCACTTCCGAGATTGCAACCCCAAGC ACAGCGGAGGCAGCAGCACCCCTGGCGGTGCGGGTGGCAGCGGCACCCCCGGCGGCTCCGGCGGCACCTC GGGCGGCGCGGGTGGCAGCAGCGCGGGCGGCAGCGGCGGTGGCAGCACCATGCCCGCCTCGGTGGCTCAC GTCCCCGCGGCAATGCTGCCGCCCAATGTCATAGACACTGATTTCATCGACGAGGAAGTGCTTATGTCCT TAGTGATAGAAATGGGTTTGGACCGCATCAAGGAGCTGCCCGAACTCTGGCTGGGCCAAAATGAGTTTGA TTTTATGACGGACTTCGTGTGCAAGCAGCAGCCCAGCAGAGTCAGCTGTTGACTCGGTTAACCTCGCAGG CGGAAAGAAATCACCCTCCCCACCCCACCCCCACCCCCAACTTCTTCGGTGTGAATTAAAAAAAAAACAA AAAAACAAACATTCCCTTAGACGCAGTATCTCGCTTTTCAGATCCTGAAAGGGTTGAGAACCTGGAAACA AAGTAAACTATAAACTTGTACAAATTGGTTTAAAAAAAAAAAAAGATTGCTGCCACTTTTTCCTATTCTT GTTTCGTTTTTTGTAGCCTTGACATTCACCTCCCTTATGTAGTTGAAATATCTAGCTAACTTGGTCTTTT TTGTTGTTTGTTTTTACTCCTTTATTTCCTCACTTTCTCCCGTGCTCAACTGTTAGATATTAAGCTTGGC AAACTGCTTAATCTTGTGGATTTTGTAGATGGTTTCAAATGACTGCGCTGCGTTCAGATTCATGAGTGAA AGGAAACATTGCATTTGTTGGCTGCATGATCTTTGAAGGGCAGATATTACTGCACAAACTGCCATCTCGC TTCATTTTTTTTAACTATGCATTCGAGTACAGACTTAAGTTTTCAAATATGCTAAACTGGAAGATTAAAC ATGTGGGCCAAACCGTTCTGGATCAGGAAAAGTCATACCGTTCACTTTCAAGTTGGCTGTCTCCCCTCCC CCATATGTACAGACAATAATAGGGTGTGGAATGTCGTCAGTGGCAAACATTTCACAGATTTTTATTTTGT TTCTGTCTTCAACATTTTTGACACTGTGCTAATAGTTATATTCAGTACATGAAAAGATACTACTGTGTTG AAAGCTTTTTAGGAAATTTTGACAGTATTTTTGTACAAAACATTTTTTTGAGAAAATACTTGTTAATTTA TTCTATTTTAATTTGCCAATGTCAATAAAAAGTTAAGAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_010828
• Insert Size: 810 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC057126, AAH57126
• RefSeq Size: 1960 bp
• RefSeq ORF: 810 bp
• Locus ID: 17684
• UniProt ID: O35740
• Cytogenetics: 10 A2
• Gene Summary: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.[UniProtKB/Swiss-Prot Function]