Gpc1 (NM_016696) Mouse Untagged Clone

CAT#: MC202606

Gpc1 (untagged) - Mouse glypican 1 (Gpc1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gpc1
• Synonyms: AI462976
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC062902 sequence for NM_016696
  CGCACACTGGGCTGAGCGGGCCGGCCGGGACCGAGGGAGGCGCGCACCGGCGGCCAGGGAGCCTCGGGCC CCGCCATGGAACTCCGGACCCGAGGCTGGTGGCTGCTGTGCGCGGCCGCCGCGCTGGTCGTCTGCGCCCG CGGGGACCCCGCCAGCAAGAGCCGGAGCTGCAGCGAAGTCCGCCAGATCTACGGGGCTAAGGGCTTTAGC CTGAGCGATGTGCCTCAGGCAGAGATCTCGGGTGAGCACCTGCGGATCTGCCCCCAGGGCTACACTTGCT GTACTAGTGAGATGGAGGAGAATTTGGCCAACCACAGCCGAATGGAGCTGGAGAGCGCACTCCATGACAG CAGCCGCGCCCTGCAGGCCACACTGGCCACCCAGCTGCATGGCATCGATGACCACTTCCAGCGCCTGCTG AATGACTCGGAGCGCACACTGCAGGAGGCTTTCCCTGGGGCCTTTGGGGACCTGTATACGCAGAACACTC GTGCCTTCCGGGACCTATATGCTGAGCTGCGCCTCTACTACCGTGGGGCCAACCTGCACCTTGAGGAGAC GCTGGCCGAGTTCTGGGCACGGCTGCTGGAGCGCCTCTTCAAGCAGCTGCACCCCCAGCTGCTGCCTGAT GACTACCTGGACTGCCTGGGCAAGCAGGCGGAGGCACTGCGGCCGTTTGGAGATGCCCCTCGAGAACTGC GCCTGCGGGCCACCCGTGCCTTTGTGGCTGCACGTTCCTTTGTGCAGGGCCTGGGTGTGGCCAGTGATGT AGTCCGGAAGGTGGCCCAGGTACCTCTGGCCCCAGAATGTTCTCGGGCCATCATGAAGTTGGTCTACTGT GCTCATTGCCGGGGAGTCCCGGGCGCCCGGCCCTGCCCCGACTATTGCCGAAATGTGCTCAAAGGCTGCC TTGCCAACCAGGCCGACCTGGATGCCGAGTGGAGGAACCTCCTGGACTCCATGGTGCTCATCACTGACAA GTTCTGGGGCCCGTCGGGTGCGGAGAGTGTCATTGGCGGTGTGCACGTGTGGCTGGCGGAGGCCATCAAC GCCCTCCAGGACAACAAGGACACACTCACAGCTAAGGTCATCCAGGCCTGTGGAAACCCCAAGGTCAATC CCCACGGCTCTGGGCCCGAGGAGAAGCGTCGCCGTGGCAAATTGGCACTGCAGGAGAAGCCCTCCACAGG TACTCTGGAAAAACTGGTCTCTGAGGCCAAGGCCCAGCTCCGAGACATTCAGGACTTCTGGATCAGCCTC CCAGGGACACTGTGCAGTGAGAAGATGGCCATGAGTCCTGCCAGTGACGACCGCTGCTGGAATGGAATTT CCAAGGGCCGGTACCTACCAGAGGTGATGGGTGACGGGCTGGCCAACCAGATCAACAACCCTGAGGTGGA AGTGGACATCACCAAGCCAGACATGACCATCCGCCAGCAGATTATGCAGCTCAAGATCATGACCAACCGT TTACGTGGCGCCTATGGCGGCAACGACGTGGACTTCCAGGATGCTAGTGATGACGGCAGTGGCTCCGGCA GCGGTGGCGGATGCCCAGATGACACCTGTGGCCGGAGGGTCAGCAAGAAGAGTTCCAGCTCCCGGACCCC CTTGACCCATGCCCTCCCCGGCCTGTCAGAACAGGAGGGACAGAAGACCTCAGCTGCCACCTGCCCAGAG CCCCACAGCTTCTTCCTGCTCTTCCTCGTCACCTTGGTCCTTGCGGCAGCCAGGCCCAGGTGGCGGTAAC TGCCCCCTATCCCCAAGGACTGTCTTGGCCAAAACATGCAACAGACCATATTTAATTCCCTTGGCCTTTT GAGGTCCAGGGCAGGATAAGGAGACAGTAGCTCTGAGTGCTGGGGCAGGGTGCATGGGGGGGTCCTGGCC TCCTGGGTCTGGCCACGCCTGTCACCCTAGCTTTTAATTTTGTATCAGGTCAGCTGCGAGCCAGTGTCCC CAAAAGCCATGTATTTCAGGGACCTCAGGGGCACCTCTGGCTGCACACTCCTCCCCTACCCTCCTGCACC ACCCCCAGAAGCTCATGAGGCCAACCAGAAGGGCGGCTGTTAGCTACAACCCAACGGAGACCTCAAGTGA GCCTGTGCCTTCCTCTCCTGCCTCTTCCCGCTGGGGACTCCCTACCAGACCCCATGGGCCACAGATGTCA GAAATTGAGGCCCATCCTGCAGCTCCCCAGGAAGCCTGCAAGGGATGCCAGTATGTTGCTGTCCAGGCTC TGGCAGGGCCTTCAAGTTTATGCATGATACCTTCTACTCAGAAGAAGCTCTGCAGCCAGGATCCCCACAC ACAGCAGACCAGGACCCTGTACCACTGTGGAGCTCAGTGAATCTGGTTCTCAAAAAAAGACCCACTGTGG GATTCTCTAGTATGACGTAGGTGAGGTGGGAGGTGGCAGCTGGCACAGCCATACTACGCTCAACTCTTCC ACACTGTTTGAGGGTATGTTCCGTCCCCTCAGATGGGCTCACAAAGACTGGCCTTGGTGGTCCACATGAG GAGCCTCACTTCAGGGGAACAGCCAGCTACATCTAGCCCCTACCCCACTTAGAAAGGTCACCTGGCCATG GGGATGCTGGGTGGCTGGTGAAACTTTAGCTCAGGGTCAATGAGACCTGGCACTGCAGGTCAAGAGGATG CCTGGGCCCCTTCCTGACCCAGGCAGCTCTGCAGGAGCTGGGGCAGCATTGACAGTCAAGGGCTTTTACA GACATGCACATTCAGACCCTCAGTGTCCTTGTCCACTGAGCGCTACATCTCCATCTTCCTTGACAGCACT GGAGAGGCTCAGGGCACCACTTGGAATCTGGTTTCCTCCTATGGCCTCGAGACCTGGGGGCACCTGGCTT ACCAAGGCTGTCAAGGCTCCATCTTCCCTTCCAGGGCCTAGGGGATGCTGAGTTGCTATATCCAGGAAGG CAGTGGTCCTGACATGCAGAAGGCCTGGAAAAAAGGCTGCTTACCGCTTTTTTTTTTTTTTAATTTTAAT TTTTTTTTTTTAACTTTCTTTTAGTCACTGGGTTAGAGAGGCTATTGCCAGCACAGCACCAAGGCCTGCC CAGTAGTCAGGTCCCCTGGTCCAGGATGGGTATTCTCCATAATTGGTCTGTGGGTTTGTTGGGCCCATGC CCTGAGCACACTCAACCCAGCCACAGCCCTGCTAGTGCCACTCAAGCAGGGGCACTGGGAGCTAGACCTG GGCTCTGAGATGAGTGCCTAGGTGTCAGGACAGCAGCACCCATGCTGTACAGGGCAGCCGGGACAGTGGC CAGGGTACTGGGTCCTTTCTCTGTCACTCGGTGTCAGTGGATAATGTGTGTTCTTTGAGTCCTTGTATGA ATTAAAGGCTGGGGACCTACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_016696
• Insert Size: 1674 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC062902, AAH62902
• RefSeq Size: 3410 bp
• RefSeq ORF: 1674 bp
• Locus ID: 14733
• UniProt ID: Q9QZF2
• Cytogenetics: 1 D
• Gene Summary: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Binds Cu(2+) or Zn(2+) ions.[UniProtKB/Swiss-Prot Function]