Twsg1 (NM_023053) Mouse Untagged Clone

CAT#: MC202531

Twsg1 (untagged) - Mouse twisted gastrulation homolog 1 (Drosophila) (Twsg1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Twsg1
• Synonyms: 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; Tsg; Twg
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004850 sequence for NM_023053
  CCCACGCGTCCGCGCGGCGCCGGGGTTCGCGGGAGCTGCTTGGAGGCTCGGCGGCCGGGAGGAGGCCGGG GCCACGCTTCTTGGAAGCTACTGAGTGACTTCTTTGAAGAACCATGAAGTCACACTATATTGTGCTAGCT CTAGCCTCCCTGACGTTCCTGCTGTGTCTCCCCGTGTCCCAGAGCTGTAACAAAGCACTCTGTGCCAGCG ATGTGAGCAAATGCCTCATTCAGGAGCTCTGCCAGTGCCGGCCTGGAGAAGGGAACTGCCCCTGCTGTAA GGAGTGCATGCTGTGCCTCGGGGCCCTGTGGGACGAGTGCTGCGACTGTGTCGGTAGGTGCAACCCTCGG AATTACAGCGACACCCCGCCCACATCCAAGAGCACCGTGGAGGAGCTGCACGAGCCCATTCCGTCCCTGT TCAGGGCGCTGACGGAGGGCGACACCCAGCTGAACTGGAACATCGTCTCCTTCCCTGTGGCAGAGGAGCT GTCACACCATGAAAACCTAGTCTCCTTCCTAGAAACTGTGAACCAGCTGCACCACCAAAACGTGTCTGTT CCCAGCAACAATGTCCACGCCCCCTTCCCCAGCGACAAAGAGCGCATGTGCACAGTGGTTTACTTTGATG ACTGCATGTCCATCCACCAGTGTAAGATATCCTGCGAATCCATGGGTGCATCCAAGTATCGCTGGTTTCA CAACGCCTGCTGCGAGTGCATCGGTCCAGAGTGCATTGACTATGGGAGTAAAACTGTCAAGTGTATGAAC TGCATGTTTTAAAGAGGGGGAAGAAATGCAAACCAAAGCAGTAAGTCATGAAGTGTGCAGAAATCTTGGT TCTGGTATGCTAGGAGTGTGTTAAGTTATATGATTGTAACTGTGCTTTTTATATCTGGTGCCTATTAGTG TAGGTCTTTTCCATTGGATTCAATGGAACTTTAGTCACATGAGGATCGGGAGTTCAGAGGAGTCCTGGGA AAACCTGACATGCTGACAGAAGGTGCCGTCTTCTTCCAGCTTTCCAAACACTTCTCGTTTTGAACGTGAT AGCACAAGCCTGGTACATGTGTGGTTCTCACCTGCCAGTTGTAGAACACTAGGTCCCTATAGTCACACAT CTCTTAATTGTGCCTTGGCTGGCTTACCTGTTTTGTATGAGTAAATATTACAGTTTATAATTCTAACAAC TCACATTCAAGCCATGCTGAAACTTAATTTCAAACCACTTTACATTGGTTTTAGAAAGTAAATATTTACT ATATTTTACAACAGAAGAGTTTTGCCTAGGGCCAGCGAGCTGACTCAGTGGATAAAGGCGCTTGCTACCA AGCCTGATAACCTGAGTTCCATCCCCAGAGCCCGTACAGTGGAAGGACAGGACCAGCTGCTGGGAGTTGT CCTCTGACCTCCAGACAGGCACAGTATCATGCGTGGAGGTGTGCTTGTGTGTGCACACACATAACTAACT GTTTTTAAAAATATAAACCTCTTACATGGTGAAATCTAAATCTGTCGTGTAGCTCTCACACTGACAGTGG TTTGGATGTTATGTCCCCTGTCCGCCTGTAGTGCTGGTGTGGTGAGACACAGAGTCGTCACTGCTCTGGT ATAGAAGAGTTTTGTCTACCAAGAGTGTCATGGCATACCTTTGGAACTTCATCAAATGCACTTGAGGATG ACCTGGGTCAGGAAGTAGCCAGGTAAAAGCAGCGGGACTGTAGGCGATGCTCCATTAGACTCCGTGCAGA GCAGCAGGTGCACAGCATAGCTGGGTGTGCGGCTGACCAGGAGAGGGTCTGACTCCGCACCAGCAGAACA GCAGGGTCTCCAGCACGTGTGGGAAGCACGTGGGAGAGGGTTGAGGAAGGATGCACAGATGTGGACAGAG AAGCATAAAAATGTCGGGAACTCCTAGTAGGGTCCACCTTAAAATCGCTTTATAGTCTCTGGCTTTATTA CTCTGTAAGATTACACTTGTTTCTGGATATCTGAATCCAAATAAGCATCATATTTTAAGAAGCTCTGTTT CTGAACTTCCAGGGGGAAATCTGTTTAATGTGTTTACTCCTAGCATACTACAGAATTTTCTAGCTCTATA GCTTCTTACCTAGCGTTTCCATAGTGCTGAGCTTCATTACTACACGCCCTTCCTAGTAATAAAATTCTCA CCTTCAAGCATGAATCAAAAACAAATATCTATAATACACAGGTTCAATTTTATAGAATTGCTATTTTCTC TAGTGCATATCTCATTAAAAGTAACTTTTTAGGAATAATCTTTATATGGGTACATATTTTGGTACATAAA ATAGAAAATGTTCTTAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_023053
• Insert Size: 669 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004850, AAH04850
• RefSeq Size: 2350 bp
• RefSeq ORF: 669 bp
• Locus ID: 65960
• UniProt ID: Q9EP52
• Cytogenetics: 17 35.26 cM
• Gene Summary: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.[UniProtKB/Swiss-Prot Function]