Lingo1 (NM_181074) Mouse Untagged Clone

CAT#: MC202498

Lingo1 (untagged) - Mouse leucine rich repeat and Ig domain containing 1 (Lingo1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lingo1
• Synonyms: 4930471K13Rik; AV148400; LERN1; LINGO-1; Lrrn6a; UNQ201
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC052384 sequence for NM_181074
  TGAGTCTGTGGGCTGCAAAACTCTCAGGGCTCTGACCGGTCCAGGCCTGACCAGTCTTGAGCGGATTCCT GCCCCCACCTGGTTACAGAATCTCCTTGTGCTTCAGGATTCGGTCAAGCATTGGACCAATCACGTGCATG CTGAGACTGAGCCCCGAAGGCTGCTGTGTCCTCAGGCCTTTGGCAGCCCCTCTGCTTGGCTCCCTGTGCC ATCTGACCCAGGAGTCACGTGAGCCTCCCTCTGGGATCTGGCATGAAGGAGAAATGGATTCTGGCTTTCC CGCTCTGGCTTTCCCTGACTTCTCCAGAATCTAAGAAGTGTCCTGAGGCATCTCTTGCTCTACCTCAGCC CAGAATCCCTGAGGATCCATCCAGAAATCCAACGACTTCAAGACCTAAAAACATCAGGCCCCTCTCCCTG GACACAGACTTGACAGAAGTGGCCAGTTCATCAGGTGAGCGAGAGGATGCTGGCAGGGGGTATGAGAAGC ATGCCCAGCCCCCTCCTGGCCTGCTGGCAGCCCATCCTCCTGCTGGTACTGGGCTCAGTGCTGTCAGGCT CTGCTACAGGCTGCCCGCCCCGCTGCGAGTGCTCAGCGCAGGACCGAGCCGTGCTCTGCCACCGCAAACG CTTTGTGGCGGTGCCCGAGGGCATCCCCACCGAGACTCGCCTGCTGGACCTGGGCAAAAACCGCATCAAG ACACTCAACCAGGACGAGTTTGCCAGCTTCCCACACCTGGAGGAGCTAGAACTCAATGAAAACATCGTGA GCGCCGTGGAGCCAGGCGCCTTCAACAACCTCTTCAACCTGAGGACTCTGGGGCTGCGCAGCAACCGCCT GAAGCTTATCCCGCTGGGCGTCTTCACCGGCCTCAGCAACTTGACCAAGCTGGACATCAGTGAGAACAAG ATCGTCATCCTGCTAGACTACATGTTCCAAGACCTATACAACCTCAAGTCGCTGGAGGTCGGCGACAACG ACCTCGTCTACATCTCCCATCGAGCCTTCAGCGGCCTCAACAGCCTGGAACAGCTGACGCTGGAGAAATG CAATCTGACCTCCATCCCCACGGAGGCGCTCTCCCACCTGCACGGCCTCATCGTCCTGCGGCTACGACAT CTCAACATCAATGCCATCAGGGACTACTCCTTCAAGAGGCTGTACCGACTTAAGGTCTTAGAGATCTCCC ACTGGCCCTACCTGGACACCATGACCCCCAACTGCCTCTACGGCCTCAACCTGACATCCCTATCCATCAC GCACTGCAACCTGACAGCCGTGCCCTATCTGGCAGTGCGTCACCTGGTCTATCTCCGTTTCCTCAACCTT TCCTACAACCCAATCGGTACAATCGAGGGCTCCATGCTGCATGAGCTGCTGCGGTTGCAGGAGATCCAGC TGGTGGGCGGGCAGCTGGCCGTGGTGGAGCCCTATGCCTTTCGTGGGCTCAACTACCTGCGTGTGCTCAA TGTCTCTGGCAACCAGCTGACCACCCTGGAGGAGTCAGCCTTCCATTCGGTGGGCAACCTGGAGACGCTC ATCCTGGACTCCAACCCACTGGCCTGTGACTGCCGGCTGCTGTGGGTGTTCCGGCGCCGCTGGCGGCTCA ACTTCAACAGGCAGCAGCCCACCTGCGCCACACCTGAGTTCGTCCAGGGCAAAGAGTTCAAGGACTTTCC GGATGTACTCCTACCCAACTACTTCACCTGCCGCCGGGCCCACATCCGGGACCGCAAGGCACAGCAGGTG TTTGTAGATGAGGGCCACACGGTGCAGTTTGTATGCCGGGCAGATGGCGACCCTCCACCAGCTATCCTTT GGCTCTCACCCCGCAAGCACTTGGTCTCGGCCAAGAGCAATGGGCGGCTCACAGTCTTCCCTGATGGCAC GCTGGAGGTGCGCTACGCCCAGGTACAGGACAACGGCACGTACCTGTGCATCGCAGCCAATGCTGGCGGC AACGACTCCATGCCCGCCCACTTGCATGTGCGCAGCTACTCGCCTGACTGGCCCCATCAACCCAACAAGA CCTTCGCCTTCATCTCCAACCAGCCAGGCGAGGGAGAGGCCAACAGCACCCGCGCCACTGTGCCTTTCCC CTTCGACATCAAGACGCTCATTATCGCCACCACCATGGGCTTCATCTCCTTCCTGGGCGTTGTCCTATTC TGCCTGGTGCTGCTGTTTCTATGGAGCCGGGGCAAAGGCAACACAAAGCACAACATCGAAATTGAGTATG TGCCCCGGAAATCGGACGCAGGCATCAGCTCAGCTGATGCACCCCGCAAGTTCAACATGAAGATGATATG AGGACGGGGCAGGGTGGGGGCACAGGGACCCCCCACCCTCAGTGGAAACACTGGGCAGGGAAGGTGCCTG GCTGCTGCCTTCCCACCTCCTCCCTGCCCTCCTCACACACTCTCCCCCTCCCCACACTCGCCTCGCCCTC ACCGCCTGCCCTCCTTCTACCAGGATTTCAGAAGGCCAGGCCTGAGGACCCCACCTGCACAGGGGCCAGA GTTGACAAAGCCGACGAACCAACACGCGGCAGAGTCAATAATTCAATTAAAAAAAAAGTTACAAACTTCC TCTGTAACTTGGGTTTCAATAATTAATGGATTTTTATGAAAACTTGAAATAATAAAAAGAAAAAAACTAT TTCCTATAGCTAGTCGGAATGCAAACTTTTGACGTCCTGATGGCTCCAGGGCCTTCTTCCAACTCAGTTT CTTGTTTTTCTCTTCCTCCTCCTCCTCTTCCTCCTCTCTCTTCTCTTCCCCTGTGGGGAGGGATCACTCA GGAAAACAGGGAAGGAGATTCCAGCCCCACCCTCTGGCCCACTCTGCTGGGCGCCATTTGGAGCCATGGG TGCCAGCTCAGCTCCAGGCCCAGCTCCAGCTGTTTTTTTGGCAGGAAGTAGGGGAGGGGATAGGACTGCC CAGGGGGGATGGGGTTTGTCTGCTGGATGTCAGGCAGCACTACCAAGGAGAGGTGGGGGTCAGGCTCGGG TGTGGCTGAAACTGGGATGGGCTGGGGTCCTCCTGGGGAACAGCACGGTCAGTGGAAAGAGTCAGGAGCC AGAGGCAGGCCGATTCCTCTCCTCTGGTCCCAGCTCTGCTGCTCACTGTTGTGTGACCTCCTTGCAGGTC GCTGGCCCCTCTTGGGCCTCAGTCTCCACATCTGTACAAATGGGAACATTTATCCCTGCCCTGCCTACCT CACAGGGCTGTTGTGAGGAACTGATGAGATGATGTATGTGAAACACTTTGTAATCTGTAAAGCGCTGTGC ACATGAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_181074
• Insert Size: 1845 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC052384, AAH52384
• RefSeq Size: 3321 bp
• RefSeq ORF: 1845 bp
• Locus ID: 235402
• UniProt ID: Q9D1T0
• Cytogenetics: 9 B
• Gene Summary: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.[UniProtKB/Swiss-Prot Function]