Ctnna2 (NM_009819) Mouse Untagged Clone

CAT#: MC202432

Ctnna2 (untagged) - Mouse catenin (cadherin associated protein), alpha 2 (Ctnna2), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ctnna2
• Synonyms: AI481747; Catna; Catna2; cdf; chp
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC079648 sequence for NM_009819
  GGAGACCCGGGCGGAGCGGGCGGCACCGCACCTCGGCCAGAAGCAGCTGCAGCAGCTGCCCTAGTCCCCA CCGCCGCCTCTCCAGCAGCTTCTGTCATTCCGCGCCAGCTGCTGCAGACAGAGGACGAGGAGGAGGAGGC GAGAAACTCCCACCGACCCACAGAGAGGCCGTGAGACCAGTTGTTAGCATTCAAGTCAGGAGGCTCATAG CTCCAGTGCCAGGAGGTTTTACTATGACAGATATTCACTCAAGCTACACATACACAGGGAGCATGACTTC GGCAACTTCACCTATTATTTTAAAATGGGATCCCAAAAGTTTGGAAATCCGGACACTCACAGTGGAAAGA CTATTGGAGCCACTTGTGACACAGGTGACAACACTTGTCAACACAAGCAACAAAGGTCCGTCTGGTAAAA AGAAAGGGAGGTCAAAGAAAGCCCATGTGCTGGCAGCATCTGTAGAACAAGCTACTCAGAACTTCCTGGA AAAGGGTGAACAGATCGCTAAGGAGAGCCAAGACCTCAAAGAAGAGTTAGTGGCTGCTGTAGAGGATGTG CGGAAGCAAGGTGAGACAATGCGGATTGCCTCCTCAGAGTTTGCAGATGACCCTTGCTCTTCTGTCAAGC GTGGCACCATGGTGCGTGCAGCACGGGCTCTGCTATCGGCTGTGACACGCTTGCTCATCCTGGCCGACAT GGCAGATGTCATGAGGCTTTTATCGCATCTGAAAATTGTCGAGGAGGCCTTGGAAGCAGTCAAAAATGCC ACAAATGAACAAGACCTTGCAAACCGATTTAAAGAGTTTGGGAAAGAGATGGTGAAACTGAACTATGTAG CAGCAAGACGGCAGCAGGAGCTCAAGGACCCTCACTGTAGGGATGAGATGGCTGCAGCCCGTGGAGCCCT GAAGAAGAATGCCACCATGCTGTACACAGCCTCCCAAGCCTTCCTCCGGCATCCAGATGTTGCTGCTACA AGAGCCAACCGAGATTATGTATTTAAACAAGTCCAAGAGGCCATAGCTGGCATCTCCAGTGCTGCTCAGG CCACCTCCCCCACCGATGAAGCCAAAGGCCACACAGGCATCGGCGAGCTGGCTGCAGCCCTGAATGAGTT TGATAATAAGATCATCCTGGACCCCATGACATTCAGCGAGGCCAGGTTCCGACCATCCCTGGAGGAGAGA CTGGAGAGCATCATCAGTGGGGCTGCTCTCATGGCAGATTCCTCCTGCACACGTGATGACCGCCGTGAGC GTATTGTGGCCGAGTGCAATGCAGTTCGACAGGCACTCCAGGACCTGCTAAGCGAGTACATGAATAACAC TGGAAGGAAAGAGAAAGGAGACCCTCTCAACATTGCGATTGACAAGATGACCAAGAAAACAAGAGATCTG AGGAGACAGCTTCGGAAAGCTGTGATGGATCACATCTCAGATTCTTTCTTGGAAACCAATGTCCCCTTGC TGGTTCTCATTGAGGCTGCGAAGAGCGGGAATGAGAAGGAGGTGAAGGAATACGCCCAAGTTTTCCGTGA ACATGCCAACAAGCTGGTGGAGGTTGCCAATTTGGCTTGTTCCATCTCCAACAATGAGGAAGGGGTGAAA TTAGTCAGAATGGCAGCCACCCAGATTGACAGCCTGTGTCCCCAAGTCATTAATGCTGCCCTCACACTGG CTGCTCGGCCACAGAGTAAAGTTGCTCAGGACAACATGGATGTCTTCAAAGACCAGTGGGAAAAGCAAGT CCGTGTGCTCACTGAGGCAGTGGATGACATCACCTCTGTGGATGACTTCCTCTCTGTCTCAGAAAACCAT ATCTTGGAGGATGTGAACAAATGTGTGATTGCCCTGCAAGAGGGAGATGTGGACACACTGGATCGCACAG CTGGGGCCATACGGGGCCGGGCAGCCCGGGTCATTCACATCATCAATGCAGAGATCGAGAACTATGAAGC TGGGGTCTATACAGAGAAAGTGCTGGAAGCCACAAAATTGCTTTCAGAAACAGTGATGCCACGCTTTGCT GAACAAGTTGAGGTGGCCATCGAAGCCCTGAGCGCCAATGTCCCTCAGCCATTCGAGGAGAACGAGTTCA TCGATGCCTCGCGCCTGGTGTATGACGGTGTTCGGGACATCAGAAAGGCTGTGCTGATGATCAGGACTCC AGAAGAGCTAGAAGATGATTCCGACTTTGAGCAAGAGGATTATGTGCGGAGTCGGACAAGTGTTCAGACA GAGGACGACCAGCTCATTGCTGGACAGAGTGCACGGGCCATCATGGCGCAACTACCACAGGAGGAGAAAG CAAAAATAGCTGAACAGGTGGAGATTTTCCACCAAGAAAAAAGCAAGCTGGATGCTGAAGTGGCCAAGTG GGATGACAGCGGCAATGACATCATTGTGCTGGCCAAGCAGATGTGTATGATCATGATGGAGATGACAGAC TTCACAAGAGGCAAAGGCCCACTGAAAAATACATCTGATGTCATTAATGCTGCCAAGAAGATTGCAGAAG CAGGCTCTCGAATGGACAAATTAGCGCGCGCTGTGGCTGATCAGTGTCCTGATTCAGCATGTAAGCAGGA TTTATTAGCCTACCTTCAGCGGATTGCTTTGTACTGCCATCAGCTTAACATCTGCAGCAAAGTGAAGGCC GAGGTTCAGAACCTAGGAGGAGAGCTCATTGTGTCAGGGACAGGAGTTCAGAGCACTTTCACTACCTTTT ATGAGGTAGATTGTGATGTCATAGATGGGGGCAGGGCTAGTCAACTTTCTACCCACCTCCCAACCTGTGC TGAGGGAGCTCCAATCGGGAGTGGAAGCAGTGACTCCTCCATGCTGGACAGTGCTACATCACTCATCCAG GCAGCCAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCGTCTTATGTAGCCTCAACTAAATACC AGAAGGTCTATGGAACAGCAGCTGTCAACTCTCCAGTTGTGTCTTGGAAGATGAAGGCTCCTGAAAAGAA GCCCCTTGTGAAGAGAGAAAAGCCTGAAGAATTCCAGACAAGAGTTAGACGGGGGTCTCAAAAGAAACAC ATTTCACCTGTGCAGGCTTTAAGTGAATTCAAGGCAATGGATTCCTTCTAGGACAATAGGCTACAAACAA GAAAGCTTTTTCTTTCCCTCCTCCCCCTTTCTTTTTCATTTTGATTCCATTTTTTGTAAGCATACCTGCT GACTTGTCTGCCTCTGGCATGGGGAAATTAAGAGAACAGTGTCTGTTTGCATGTTAGACGAGATGAGATC AATGCTGCTGGTCTATCAGTAGCCTCGGAAGGGGACAGGTGACAATTTCTGTCCTGAGGTGGAACAGAGC TGTCCTTTGCAACATTCTCTTAAAGTTGGGCAAAGAGTTCACACTGTGATGTTCACGGGAGTGGGAGGGA TGGGGAAAATAAACTTAACTCTACAAAAGCAAACTCTAATGCATGCAAGAACCATTAGGTTGGCAGGTAT ATTCATAAGTGAAAAACCTGGAAGTGTAATGGTAGAACATAAAACCTGTACTGCTTCTGTTTGAGTGCAA AACTGTACTAGCCAATACGCTGAAGTGTGTGGCCCACAAATTGAAATTTTAACCTCAATGTCCTGTATCC ATGCTCTCATGTGGATTCTTAACTGAGGAGAAACTAACTCATCCCGTCTCAAATGTTTCTTTAATCTGCA TTCTGTTCTTTCTTCCTGGTAGTGCCATTACTAGTGTTCCTCTTATTTTCTCCCCTCTGCTGAAGACAAT AAATATTCCTTTGAGACCCGTGGATCCTTCTGCGGACCCTAATGACACAAAGTGGAGCTCAACTGTCCTC CCTTCTATTTCTTTCTTTCTAAACTTGAACTCTGACTTTGCTAGACATAGAAGGCTCAGTGGTGGAACGT TAGCGAAATGGAGATTGACAGTATGTGAAGGCTTAGAGGCAAATGCATAGGTGTGTAGCTGAGAGTGCTG GTATCTAATATACCATTGTATTCACTGACACAAAATAAACACATTTAATCTTGAAAAAAAAAAAAAAAAA AA
• Restriction Sites: AscI-NotI
• ACCN: NM_009819
• Insert Size: 2859 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC079648, AAH79648
• RefSeq Size: 4062 bp
• RefSeq ORF: 2859 bp
• Locus ID: 12386
• UniProt ID: Q61301
• Cytogenetics: 6 33.54 cM
• Gene Summary: May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (PubMed:12123610, PubMed:15034585). Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability (By similarity). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (PubMed:12089526).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 2 and 3 both encode isoform 2.