Gpm6a (NM_153581) Mouse Untagged Clone

CAT#: MC202182

Gpm6a (untagged) - Mouse glycoprotein m6a (Gpm6a), (10ug)


  "NM_153581" in other vectors (4)

Reconstitution Protocol

USD 300.00

In Stock*

Size
    • 10 ug

Product Images

Frequently bought together (3)
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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Gpm6a
Synonyms Gpm6; M6A
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC029683 sequence for NM_153581
AGGACTTGCCCAAGCCACTGCTGCTGGAGCTGCCCAGGGAAAAAAGGCACACGCTTTTTTGACATCTAAT TGAGCTTTTGACTAATACCGTGCGCCAGATTCTCCTGAAGAAAGGTAGCCATGGAAGAGAATATGGAAGA AGGACAGACACAGAAAGGGTGCTTCGAGTGCTGCATTAAATGCCTGGGAGGTATTCCCTATGCTTCTCTG ATTGCAACCATCCTGCTGTATGCAGGCGTTGCCCTGTTCTGTGGCTGTGGCCATGAAGCCCTTTCTGGAA CAGTCAACATTCTGCAGACCTACTTTGAGTTGGCAAGGACTGCTGGAGACACACTGGATGTTTTCACTAT GATTGACATCTTTAAGTATGTGATCTATGGCATTGCGGCTGCTTTCTTTGTCTATGGCATTTTACTGATG GTAGAAGGTTTCTTCACAACTGGGGCTATCAAAGATCTCTATGGAGACTTCAAAATCACCACCTGTGGCA GATGTGTGAGCGCTTGGTTTATCATGCTGACATACCTCTTCATGTTGGCCTGGCTGGGAGTCACAGCTTT CACCTCACTGCCCGTGTACATGTATTTCAATGTGTGGACCATCTGCCGGAACACCACTCTAGTGGAGGGA GCAAATCTCTGCTTGGATCTGCGTCAGTTTGGGATTGTGACAATTGGAGAGGAAAAGAAAATTTGTACTG CCTCTGAGAACTTCCTGAGGATGTGTGAATCTACTGAGCTGAATATGACCTTCCACTTGTTCATTGTGGC ACTTGCTGGAGCTGGAGCAGCAGTTATTGCTATGGTCCACTACCTGATGGTTCTGTCTGCCAACTGGGCC TATGTGAAAGATGCCTGCCGCATGCAGAAGTACGAAGACATCAAGTCAAAGGAAGAGCAGGAGCTGCACG ACATCCATTCTACTCGCTCCAAAGAGCGGCTCAATGCGTACACATAAATACGCTTCTCTGTTCCTTACCA CTCGAAGGCATTGGTGTTTCATTAAGGGCCATCCAACCATCCAACCTGTGAAGAGCAAAACGAGAATGCT ACTCATCAAAGATGCGCAGGGTGACTAATGAATCACCTGAGTATAACTCTTTGCTGTTGAGCATTCCATC TTCTAATTTGTTAAATTGGAATGACCAAATCTCCTCTACAAGCTCCTATTCAGTCTTTTTTTTTAACCTC TCAAATTGATTTAGTTCTTCTGTATGATCAAAGATATTAACATTGTCCAACGCAAATCTTTGTTTGATTT TTAATCACCTCCCACATATCACACATAACACTTTTTGCATTGTTTCTTATGTTTTGGAAGAGAAAATAGC TTTTTTTATACTTTTTAGTTTTGATTTCAGTAACTAGTTTAACTACAGGTAACCTTCAAAGGGACCGTTG TACATTATGAAAGAGAGACAGAGATGGTATCATGATGACTCCGCTTGATATGGGAATCAGTCTGGAGAGA TCAGTGGCCACACGGCTATCGGCCATGGTTAATGTTTTCATCCATCTAAGGTGCAATTTCAAAATTTCTA AGGGTAGGTTAAAAAAAAGTGCTTCTTATCTTTGTTAACATTGTATTCTTTTTTCTTGATGTTCGTAAAA GGTATTTCTCTGATTACTCATGTTTATGTTGTGAGCATGTAGAAACAGTAATGCTAATGCATGGCCAGTT GCCTTCCTAAGATTGTGACACCAGGCTTACCTTTTCAAGTTTAGTATAGAAACAATTATCATGGAAATAA CTACTGTGGACTGTTGGAGAGTGATCTTTTTTTGTGATTTATGCAGTGGCTGGATTGGATCTTTTAATAT GCTAATGTGGAAAATTAATTACCTTTATGAAGGTGGTATCTTAAACATAAGCACACTAAACCCTCAAGAC TTGTTTTACCCACTTAAAACTTTTAACGGATTGCACCTCTGTAAGCTATTTCTTAAAATGTGTATGATAT ATTTGAAAAGACTTCCATTAATATAATAGCTTTGCTTGCAGCCTTCCAATCTATGTTGGTTTACCTGTAG TGTTTCTAAAGGGTGGTCAGAGGCCACTAGAGAATGTATTGTTTGGGAGTGTAGTGATATATATTTTGTG TTTTTATTTCAAGTAAGTCATTTTAACCAAATGTTCATTCACATTCATTTATAAGAAGTACCTATATCAG ACAAATTTTAAAAGAAAAACAATCAGTATTAATGGACCAAATTTCGTGTTTGTTTTAACCTTGACTCTCT TTTGATTCTTTCTAATGCTACAAGAATGCTGTGAAATGTCATTTAAAATAATGATGTAGCCTGACAAGAA ATTTTGTCAGTGTATAAACCTAGGTAGTATTGTGCACTGATTTGACCATTGTGAATTCCTCCTTCAGTGT AAGTGCATTCCCAATAAAATTTATTGAGTGAAACAATCTTTGTACAACTACTAGTCATGCATCATCAGTA ATTTTACAAGTTCTTGTAGTAGGTAGGGGGTATTACTAGCGTTTCTGTGGCATGATTATGCATTCTGTAA TATTAATTTGGGGGTCCTTTTGCTTTTTAACACTTAGATTATCTTAATGGTTCAACATTTTTCTGATATA TGCAGTATTAAAGATATTGAGCAAAAGTATTAATGGGCTTCTTTAAATTCTATATTATAGTGTTTCAGTT CTGTGTCTACAGTGTGTGATGATTTTTAAAACTGTCTTTTAAATTTATGTAATGATGTTGACATTTTGAC TTTTATTTCTGGTTTTAGAGTTTGTATTTTCATGGAGTGCTTTGTAGCAGGCATTACAAGTAATCTGTTT TGTACATAAATGTGCCAACAGCTTGATGGTGGCGTTTTTGAAATGTAGAACAAAGTGCTTGCAAAATGTA ATAAATACACTTGTGTACTTTGTGTACTTATTCTTAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_153581
Insert Size 837 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq BC029683, AAH29683
RefSeq Size 2920 bp
RefSeq ORF 837 bp
Locus ID 234267
UniProt ID P35802
Cytogenetics 8 B1.3
Gene Summary Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, PubMed:22162747 reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a function in actin-independent membrane deformation. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).

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