Cd274 (NM_021893) Mouse Untagged Clone

CAT#: MC201908

PD-L1 / CD274 (untagged) - Mouse PD-L1 / CD274 antigen (PD-L1 / CD274), (10ug)

USD 196


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Size
    • 10 ug

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Specifications

Product Data
Product Name Cd274 (NM_021893) Mouse Untagged Clone
Symbol Cd274
Synonyms A530045L16Rik; B7h1; Pdcd1l1; Pdcd1lg1; Pdl1
Vector pCMV6-Entry
Sequence Data
Fully Sequenced ORF
>BC066841 sequence for NM_021893
GCCTCATGCCAGGCTGCACTTGCACGTCGCGGGCCAGTCTCCTCGCCTGCAGATAGTTCCCAAAACATGA GGATATTTGCTGGCATTATATTCACAGCCTGCTGTCACTTGCTACGGGCGTTTACTATCACGGCTCCAAA GGACTTGTACGTGGTGGAGTATGGCAGCAACGTCACGATGGAGTGCAGATTCCCTGTAGAACGGGAGCTG GACCTGCTTGCGTTAGTGGTGTACTGGGAAAAGGAAGATGAGCAAGTGATTCAGTTTGTGGCAGGAGAGG AGGACCTTAAGCCTCAGCACAGCAACTTCAGGGGGAGAGCCTCGCTGCCAAAGGACCAGCTTTTGAAGGG AAATGCTGCCCTTCAGATCACAGACGTCAAGCTGCAGGACGCAGGCGTTTACTGCTGCATAATCAGCTAC GGTGGTGCGGACTACAAGCGAATCACGCTGAAAGTCAATGCCCCATACCGCAAAATCAACCAGAGAATTT CCGTGGATCCAGCCACTTCTGAGCATGAACTAATATGTCAGGCCGAGGGTTATCCAGAAGCTGAGGTAAT CTGGACAAACAGTGACCACCAACCCGTGAGTGGGAAGAGAAGTGTCACCACTTCCCGGACAGAGGGGATG CTTCTCAATGTGACCAGCAGTCTGAGGGTCAACGCCACAGCGAATGATGTTTTCTACTGTACGTTTTGGA GATCACAGCCAGGGCAAAACCACACAGCGGAGCTGATCATCCCAGAACTGCCTGCAACACATCCTCCACA GAACAGGACTCACTGGGTGCTTCTGGGATCCATCCTGTTGTTCCTCATTGTAGTGTCCACGGTCCTCCTC TTCTTGAGAAAACAAGTGAGAATGCTAGATGTGGAGAAATGTGGCGTTGAAGATACAAGCTCAAAAAACC GAAATGATACACAATTCGAGGAGACGTAAGCAGTGTTGAACCCTCTGATCGTCGATTGGCAGCTTGTGGT CTGTGAAAGAAAGGGCCCATGGGACATGAGTCCAAAGACTCAAGATGGAACCTGAGGGAGAGAACCAAGA AAGTGTTGGGAGAGGAGCCTGGAACAACGGACATTTTTTCCAGGGAGACACTGCTAAGCAAGTTGCCCAT CAGTCGTCTTGGGAAATGGATTGAGGGTTCCTGGCTTAGCAGCTGGTCCTTGCACAGTGACCTTTTCCTC TGCTCAGTGCCGGGATGAGAGATGGAGTCATGAGTGTTGAAGAATAAGTGCCTTCTATTTATTTTGAGTC TGTGTGTTCTCACTTTGGGCATGTAATTATGACTGGTGAATTCTGACGACATGATAGATCTTAAGATGTA GTCACCAAACTCAACTGCTGCTTAGCATCCTCCGTAACTACTGATACAAGCAGGGAACACAGAGGTCACC TGCTTGGTTTGACAGGCTCTTGCTGTCTGACTCAAATAATCTTTATTTTTCAGTCCTCAAGGCTCTTCGA TAGCAGTTGTTCTGTATCAGCCTTATAGGTGTCAGGTATAGCACTCAACATCTCATCTCATTACAATAGC AACCCTCATCACCATAGCAACAGCTAACCTCTGTTATCCTCACTTCATAGCCAGGAAGCTGAGCGACTAA GTCACTTGCCCACAGAGTATCAGCTCTCAGATTTCTGTTCTTCAGCCACTGTCCTTTCAGGATAGAATTT GTCGTTAAGAAATTAATTTAAAAACTGATTATTGAGTAGCATTGTATATCAATCACAACATGCCTTGTGC ACTGTGCTGGCCTCTGAGCATAAAGATGTACGCCGGAGTACCGGTCGGACATGTTTATGTGTGTTAAATA CTCAGAGAAATGTTCATTAACAAGGAGCTTGCATTTTAGAGACACTGGAAAGTAACTCCAGTTCATTGTC TAGCATTACATTTACCTCATTTGCTATCCTTGCCATACAGTCTCTTGTTCTCCATGAAGTGTCATGAATC TTGTTGAATAGTTCTTTTATTTTTTAAATGTTTCTATTTAAATGATATTGACATCTGAGGCGATAGCTCA GTTGGTAAAACCCTTTCCTCACAAGTGTGAAACCCTGAGTCTTATCCCTAGAACCCACATAAAAAACAGT TGCGTATGTTTGTGCATGCTTTTGATCCCAGCACTAGGGAGGCAGAGGCAGGCAGATCCTGAGCTCTCAT TGACCACCCAGCCTAGCCTACATGGTTAGCTCCAGGCCTACAGGAGCTGGCAGAGCCTGAAAAACGATGC CTAGACACACACACACACACACACACACACACACACACACACACACACCATGTACTCATAGACCTAAGTG CACCCTCCTACACATGCACACACATACAATTCAAACACAAATCAACAGGGAATTGTCTCAGAATGGTCCC CAAGACAAAGAAGAAGAAAAACACCAAACCAGCTCTATTCCCTCAGCCTATCCTCTCTACTCCTTCCTAG AAGCAACTACTATTGTTTTTGTATATAAATTTACCCAACGACAGTTAATATGTAGAATATATATTAAAGT GTCTGTCAATATATATTATCTCTTTCTTTCTTTCTTCCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTC TTTCTTTCTTTCTTTCTTTCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTTCTTTCTTTCTT TCTTTTTTTCTGTCTATCTGTACCTAAATGGTTGCTCACTATGCATTTTCTGTGCTCTTCGCCCTTTTTA TTTAATGTATGGATATTTATGCTGCTTCCAGAATGGATCTAAAGCTCTTTGTTTCTAGGTTTTCTCCCCC ATCCTTCTAGGCATCTCTCACACTGTCTAGGCCAGACACCATGTCTGCTGCCTGAATCTGTAGACACCAT TTATAAAGCACGTACTCACCGAGTTTGTATTTGGCTTGTTCTGTGTCTGATTAAAGGGAGACCATGAGTC CCCAGGGTACACTGAGTTACCCCAGTACCAAGGGGGAGCCTTGTTTGTGTCTCCATGGCAGAAGCAGGCC TGGAGCCATTTTGGTTTCTTCCTTGACTTCTCTCAAACACAGACGCCTCACTTGCTCATTACAGGTTCTC CTTTGGGAATGTCAGCATTGCTCCTTGACTGCTGGCTGCCCTGGAAGGAGCCCATTAGCTCTGTGTGAGC CCTTGACAGCTACTGCCTCTCCTTACCACAGGGGCCTCTAAGATACTGTTACCTAGAGGTCTTGAGGATC TGTGTTCTCTGGGGGGAGGAAAGGAGGAGGAACCCAGAACTTTCTTACAGTTTTCCTTGTTCTGTCACAT GTCAAGACTGAAGGAACAGGCTGGGCTACGTAGTGAGATCCTGTCTCAAAGGAAAGACGAGCATAGCCGA ACCCCCGGTGGAACCCCCTCTGTTACCTGTTCACACAAGCTTATTGATGAGTCTCATGTTAATGTCTTGT TTGTATGAAGTTTAAGAAAATATCGGGTTGGGCAACACATTCTATTTATTCATTTTATTTGAAATCTTAA TGCCATCTCATGGTGTTGGATTGGTGTGGCACTTTATTCTTTTGTGTTGTGTATAACCATAAATTTTATT TTGCATCAGATTGTCAATGTATTGCATTAATTTAATAAATATTTTTATTTATTAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
Tag Tag Free
ACCN NM_021893
ORF Size 873 bp
Insert Size 873
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq BC066841, NP_068693
RefSeq Size 3697
RefSeq ORF 873
Locus ID 60533
Cytogenetics 19|19 C1
Gene Summary The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015].
Transcript Variant:
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