Ces2c (NM_145603) Mouse Untagged Clone

CAT#: MC201775

Ces2c (untagged) - Mouse carboxylesterase 2C (Ces2c), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ces2c
• Synonyms: ACH M1; Ces; CES 2; Ces2; ces2A3
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC031170 sequence for NM_145603
  GAAACTTGGTCATCTTAGCAGCACAGACTTAGGACTGAGAGCTGATCATGACACGGAACCAACTACATAA CTGGCTGAATGCTGGGTTCTTCGGGCTGCTGCTTCTTCTTATCCATGTGCAGGGTCAGGACTCACCAGAG GCCAACCCCATCAGAAACACACATACAGGACAGATCCAAGGCAGCCTTATCCACGTGAAGGACACTAAAG CTGGTGTCCACACCTTCCTGGGAATCCCCTTTGCCAAACCTCCTGTAGGACCACTGCGATTTGCACCTCC TGAGGCCCCTGAACCATGGAGTGGTGTGAGAGATGGAACTGCACATCCGGCCATGTGTCTGCAAAATCTT GACATGCTGAATGAAGCAGGCCTGCCAGATATGAAAATGATGCTGTCTTCCTTCCCTATGTCTGAGGACT GCCTGTATCTCAACATCTACACCCCAGCCCATGCCCATGAGGGCTCTAACCTGCCTGTGATGGTGTGGAT CCATGGAGGTGCACTGGTTATAGGAATGGCTTCCATGTTTGATGGATCTCTATTGACAGTCAATGAGGAC TTGGTGGTTGTTACTATCCAGTATCGTCTGGGTGTCCTGGGCTTTTTCAGCACTGGAGACCAGCATGCCA GAGGCAACTGGGGATACCTGGACCAAGCAGCTGCCCTACGCTGGGTCCAGCAGAACATCGCTCACTTTGG AGGCAACCCTGACCGGGTCACTATTTTTGGCGAGTCTGCAGGTGGCACAAGTGTGTCTTCACATGTTGTG TCCCCCATGTCCCAAGGGCTCTTCCATGGTGCCATCATGGAGAGTGGGGTGGCCCTGCTTCCTGACCTTA TCTCTGAAACCTCTGAGATGGTTTCCACTACGGTGGCCAAGCTTTCTGGATGTGAGGCTATGGATTCCCA GGCCCTGGTGCGCTGTCTGAGAGGCAAAAGTGAAGCAGAGATTCTGGCTATTAACAAGGTCTTCAAGATG ATCCCTGCTGTGGTGGATGGGGAGTTCTTCCCCAGGCATCCCAAAGAGTTGTTGGCATCTGAGGATTTTC ACCCTGTCCCCAGCATCATTGGTGTCAACAATGATGAGTTTGGCTGGTCCATTCCTGTGGTCATGGGCTC TGCTCAGATGATAAAAGGAATAACCAGAGAGAACCTGCAGGCTGTTCTGAAGGATACAGCAGTACAAATG ATGCTGCCTCCTGAGTGTAGTGACCTGCTAATGGAAGAGTACATGGGGGACACTGAGGATGCCCAGACCC TCCAAATACAGTTCACAGAGATGATGGGAGATTTCATGTTTGTGATCCCTGCACTCCAAGTAGCACATTT TCAACGCTCCCATGCCCCTGTCTACTTCTATGAGTTCCAACATCCACCCAGCTACTTCAAGGATGTCAGA CCACCCCACGTGAAGGCTGACCATGCTGATGAGATTCCTTTTGTCTTTGCGTCCTTCTTCTGGGGCATGA AACTTGACTTCACTGAGGAGGAGGAGCTGCTGAGCAGGAGGATGATGAAGTACTGGGCCAACTTTGCACG ACATGGGAACCCCAACAGTGAGGGTCTACCCTACTGGCCTGTGATGGACCATGATGAGCAGTACCTGCAA CTGGACATCCAGCCTGCTGTGGGTCGAGCCCTGAAGGCTGGAAGGCTGCAGTTCTGGACCAAGACTCTGC CCCAGAAGATCCAGGAGCTAAAGGCTTCTCAGGACAAGCACAGGGAGCTTTAGTACCCTGTATCAAAAAA AATGTGTTTGGGGTTTAAAGTCAATAGCGCTACAAATTCCATTTATTTATTTTTATTTGTTCCAACACTT ACATAAGCATCTGTCACCTCAGTCTTTGAGCTTTCATGTATGAAAAATACTCTGTATTACTTATCATTCT GGCCAAACTTTCATTAAATTCAATAAATTCTCAAATAACACTGTGGAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_145603
• Insert Size: 1686 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC031170, AAH31170
• RefSeq Size: 1974 bp
• RefSeq ORF: 1686 bp
• Locus ID: 234671
• UniProt ID: Q91WG0
• Cytogenetics: 8 D3
• Gene Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. The transcription of this gene is regulated by several factors including HNF-4alpha (hepatocyte nuclear factor-4alpha), Sp1 (specificity protein 1), Sp3 and USF1 (upstream stimulatory factor 1). The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with several family members including a few of pseudogenes and Ces5 on chromosome 8.[provided by RefSeq, Jun 2010]