Gatsl3 (NM_028022) Mouse Untagged Clone

CAT#: MC201405

Gatsl3 (untagged) - Mouse GATS protein-like 3 (Gatsl3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gatsl3
• Synonyms: 2410008K03Rik; Castor1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC039988 sequence for NM_028022
  CGCCACCGCATCGCCTCCTGCCTAGGTCTCGCTGGCGGCCAGGCCGGGGCTGCCGTATCTGCGATGGAAC TTCACATCCTAGAGCACCGGGTGCGAGTACTGAGCATTGCCCGTCCGGGCCTCTGGCTCTACACCCACCC GCTCATCAAGCTGCTCTTCCTGCCCTGTCGCAGTCGGTGCAAGTTCTTCAGCCTGACTGAGACTCCGGAA GATTACACTCTCATGGTGGATGAGGAGGGCTTTAAAGAGCTACCCCCATCCGAGTTCCTGCAAGTGGCTG AGGCCACATGGCTGGTGATGAACGTATCTCACAGTGGCTCCGTGGTGCAGGCTGCTGGAGTAACCAAGAT TGCCCGGTCTGTCATTGCCCCGCTGGCTGAACACCATGTGTCTGTTCTGATGTTGTCCACATACCAGACA GACTTCATCCTGGTACGGGAGCAGGACCTGTCTGTGGTGATCCACACACTGGCCCAGGAGTTCCAAATCT ACCGTGAAGTAGGCGGGGAGCCTGTGCCCGTTACTGGAGACGATTCCAGCAATGGCTTTCCCCAGATCCA GCACGGGCCCAGTCCCACGGTGCATCCCATTCAGAGCCCTCAGAACCGCTTTTGTGTCCTCACACTTGAC CCTGAGACACTGCCGGCTGTCGCCACCACCCTCATCGATGTCCTCTTCTACTCCCACAGTGTCCCCAAGG AAGCGGCCTCGGGCGGTCCTGAATCAACGTCCATTCCGTTCTTCGCTTTCTCCCTCATCGAGGGGTACAT CTCCATTGTCATGGATGCAGAGATCCAGAGAAAGTTCCCCAGTGACCTCCTGCTGACCAGCTCTTCTGGG GAGCTGTGGAGGATGGTGCGCATCGGGGGACAGCCCCTGGGCTTCGATGAATGTGGGATTGTGGCCCAGA TTGCGGGTCCCCTGGCGGCTGTTGACATCTCTGCTTACTACATCAGCACATTCAACTTTGACCATGCGCT GGTTCCTGAAGACGAGATCGGCTGTGTCATTGATATTCTCCAGCGAAGGCAGGAAAGCCAGGCTTCCAAG GACCCATAGGGAAGCACCAGACCCCCAGCATTCCCGTAAAGCCCCCCGGGGCTCCAGAAACTTTTCTGAG CTTCAGAACAAGTCCCTGGTCCTGCCAAGGGATCCTGGTTCTGCTGTCTGTCTGTCAGCTGTATGGAGCT GGGACTCGTGGCCATGCCTGGTTCTGCTGTCTGTCTGTCAGCTGTATGGAGCTGGGACTCGTGGCCATGC CTGCCCACAAAAGATACCTTGGTGCTTGGGGCTTAGATCCCCGACCCAACATTTTCTATGTGACCTCAGC AATGCACAGAGCCTGCTTGCCTGCAGCTGGAGCCGCCTCTCCCCTGGCTAAGGCTCACATCCCCGGGCCG GGCTCTGACCTCCAGCCTGCACTGCTTTCCTAGCCAGATGAGTTCAGCAGTGCACTCCCTTCGCGGGACT CCGAAGGAAGAATTAAATCTCACTTTTATTTTCATGACTGTTTATATAAATAAAAGACTTGCGGATTTGT GCCCTCTGAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: EcoRI-NotI
• ACCN: NM_028022
• Insert Size: 996 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC039988, AAH39988
• RefSeq Size: 1570 bp
• RefSeq ORF: 996 bp
• Locus ID: 71962
• UniProt ID: Q9CWQ8
• Cytogenetics: 11 A1
• Gene Summary: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.[UniProtKB/Swiss-Prot Function]