Psmc4 (NM_011874) Mouse Untagged Clone

CAT#: MC200832

Psmc4 (untagged) - Mouse proteasome (prosome, macropain) 26S subunit, ATPase, 4 (Psmc4), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Psmc4
• Synonyms: CIP21; MIP224
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC012708 sequence for NM_011874
  CCACCCGTCCGCCCACGCGTCCGGGCTTGGTCACTATGGAGGAGATAGGCATTTTGGTGGAAAAGATTCA GGATGAGATTCCAGCACTGTCCGTGTCTCGGCCGCAGACCGGCCTGTCCTTTCTGGGACCCGAACCTGAA GACCTGGAGGACCTGTACAGCCGCTACAAGAAGCTGCAGCAGGAGCTGGAGTTCCTGGAGGTGCAGGAGG AGTATATCAAGGACGAGCAGAAGAACCTGAAGAAGGAATTCCTCCACGCCCAGGAGGAGGTGAAGCGGAT CCAGAGCATCCCCTTGGTCATCGGTCAGTTCTTGGAAGCTGTGGATCAGAACACAGCCATCGTGGGCTCC ACCACAGGCTCTAACTATTATGTGCGCATCCTGAGTACCATCGACCGGGAGCTGCTCAAGCCCAACGCCT CGGTGGCCCTGCACAAGCACAGCAATGCCCTGGTGGACGTGCTGCCTCCCGAGGCCGACAGCAGCATCAT GATGCTCACCTCAGACCAGAAGCCAGATGTGATGTATGCCGATATTGGAGGCATGGACATCCAGAAGCAG GAGGTGAGGGAGGCTGTGGAACTCCCGCTTACACACTTCGAGCTGTACAAGCAGATTGGCATCGATCCTC CCCGAGGTGTCCTCATGTATGGCCCTCCTGGCTGTGGAAAGACAATGTTAGCAAAGGCTGTGGCACATCA CACGACAGCTGCATTTATCCGTGTGGTGGGCTCGGAGTTTGTTCAGAAGTACCTGGGTGAGGGCCCCCGG ATGGTCCGGGATGTGTTCCGCCTAGCTAAGGAGAATGCACCTGCCATCATCTTCATAGATGAAATTGATG CCATTGCCACCAAGAGATTCGATGCCCAGACAGGAGCTGACAGGGAGGTTCAGAGGATCCTGCTGGAGCT ACTGAATCAAATGGATGGATTTGACCAGAACGTCAATGTGAAGGTAATCATGGCCACAAACAGAGCAGAC ACCTTGGATCCAGCTCTACTGCGGCCAGGACGCCTGGACCGAAAAATTGAATTCCCACTCCCTGACCGTC GCCAGAAGAGGTTGATTTTCTCCACCATCACCAGCAAAATGAACCTCTCTGAGGAGGTCGACCTGGAAGA CTATGTGGCCCGTCCAGATAAGATTTCAGGAGCCGATATCAACTCCATCTGTCAGGAGAGTGGAATGTTG GCTGTCCGTGAGAACCGCTACATTGTCCTGGCCAAGGACTTCGAGAAAGCATACAAGACCGTGATCAAGA AAGATGAACAGGAACATGAATTTTACAAGTGACCCCCTCCCCACACTTCCCCAGGCACCTGTCCCAAAGG CTAGTTTTCTCTTTACCCAGGATTGGTTTAGTCAATAAATGGACGTGATTGGAAAAAAAAAAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_011874
• Insert Size: 1257 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC012708, AAH12708
• RefSeq Size: 1406 bp
• RefSeq ORF: 1257 bp
• Locus ID: 23996
• UniProt ID: P54775
• Cytogenetics: 7 16.11 cM
• Gene Summary: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.[UniProtKB/Swiss-Prot Function]