Cldn11 (BC021659) Mouse Untagged Clone

CAT#: MC200822

Cldn11 (untagged) - Mouse claudin 11 (cDNA clone MGC:14055 IMAGE:4190031), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cldn11
• Synonyms: Claudin11, Claudin-11
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC021659
  CCACGCGTCCGCGCTGCACGCTGTCGCAGCAGTGCTCGCAGCCGCTCTCTCCCCATCTCGAGTAGCCCGG AGCCAGCGGCTCGCGAGGGCCAAGAGGGCAAGCCTAGGGAAGGCTCTGTCCAGGACGACACAGGGGGCAC AATCCGTGTGAGTCGAGCTGCGTGGACGTCGCTGCGGCCACCATGGTAGCCACTTGCCTTCAGGTGGTGG GTTTCGTCACGAGCTTCGTGGGTTGGATTGGCATCATCGTCACAACGTCCACCAATGACTGGGTGGTGAC CTGCAGCTACACCATCCCCACCTGCCGAAAAATGGACGAACTGGGCTCCAAGGGCCTGTGGGCTGACTGC GTCATGGCCACTGGTCTCTACCACTGCAAACCCCTGGTGGACATCCTCATCCTTCCAGGCTACGTGCAGG CTTGTAGAGCCCTCATGATTGCTGCCTCCGTTCTGGGCCTGCCCGCCATCTTGCTGCTGTTGACAGTTCT CCCCTGCATCCGAATGGGCCACGAGCCTGGAGTGGCCAAGTACAGGCGAGCCCAGCTGGCTGGGGTGCTC CTTATTCTGCTGGCTCTCTGCGCCATTGTCGCCACCATCTGGTTTCCTGTATGTGCCCACCGCGAGATCA CCATCGTGAGCTTTGGCTACTCGCTGTACGCAGGTTGGATCGGTGCTGTGATGTGCCTGGTGGGTGGCTG TGTCATCGTCTGCTGCTCCGGGGATGCACAGTCATTTGGAGAAAACCGTTTCTATTACTCTTCTGGTTCC AGCTCGCCAACGCATGCCAAGAGTGCCCATGTCTAAGAGGGCTGCTCCACTGCCCGCCGAGGTGCTGTAA ATGCTGGGCCTGGGCCCTGGGTTTGCTCGCCACAGTGGGGAGAAGCCCACTTCCCTGCCAGGCACTAAAG CCAAAGTTCTAGAAAGTATCCTGCCCCGGCATTTTGAAGTCGTAACACCCCACCCACCCACCCACCACTT CTTGGCTGCCTTAAAAGAAAGCTCTAGCTCAGTTAATGCCCACATAGTTTTCTCCTGGAGTTGCGGGCTG TGGCTGTTTGCTCTTTCCTCGGGCATTCCATTGTTGTTGATTAAAAAAATATTTTGTTTCTCTCTTAAAT TCAAATGTCTTGGGAACATTGCTGACTTGGGTGTGGATTGGGAAAGAAATAAAAGATGCTTTTCAAAGGG TTACCAACGACAGTGGAAGCCTTATAGAGACAGCTCTCTTCTCCCTTTCGGCTTAGTTTCAAGGTCACTT ATATATAAGAGATAGAAATGGATAGATTGGGAACACGGGTGGGAGGGGAACTCAGAGCTTTCCCTCCACG GGAAGCTTCTCTTTTATAAGTTGAGGGGTTGGGTGTCTTTTTTTTTTTTTAGTTTGCGATTTTACATTTT TCTGTACGTACTTTTTCAAGATTGATCATTTTTATAACCACGGGTTTCCTGAAAATTCTCAATTCACCAA TATGAAGGAAATGAACCAAGCAGACGTTAATATGCAATAAATAATAGTACGAAGATTATAACTTTAACTG ACTGCCCACGGTTTCCAGGTTTGTATGCTATAGTTTTTAATCCTATGGTTGCATATGCTTCAAATTAACA CATTTAAAAATCTTTTCTCCCCTTCTATTTCTGTCTCCATTCTGTTAGAGACCATGAAGCAGTATTGTTT AACATAAGTTGTACTGTTAAGTTTGGCTTCATGGGTGTAAACACCAATGGTCTGTCAGTGTCTAAGACTC TGGATACTGCAAGCTCCGTCCGGTGCATTTGTTCAGGTAAAATCTGTGCAATAAAATAACAAACTGTCTC CAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC021659
• Insert Size: 624 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC021659, AAH21659
• RefSeq Size: 1848 bp
• RefSeq ORF: 624 bp
• Locus ID: 18417
• Cytogenetics: 3 15.14 cM
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of CNS (central nervous system) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. The basal cell tight junctions in stria vascularis are primarily composed of this protein, and the gene-null mice suffer severe deafness. This protein is also an obligatory protein for tight junction formation and barrier integrity in the testis and the gene deficiency results in loss of the Sertoli cell epithelial phenotype in the testis. [provided by RefSeq, Aug 2010]