Angptl4 (NM_020581) Mouse Untagged Clone

CAT#: MC200784

Angptl4 (untagged) - Mouse angiopoietin-like 4 (Angptl4), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Angptl4
• Synonyms: Arp4; Bk89; Fiaf; Hfarp; Ng27; Pgar; Pgarg; Pp1158
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC006611 sequence for NM_020581
  ACGGGCTCCAGATCTTCTTCTGCACCAGAGCAAGTCTAAGTCTGAGCCGGCTCCCCCAGAACTCCAGCTG CTGGGTCTTGAACTCCTGCGTTCCGGAGTCCTAGCGTTGCTGCACCCAAGGCCACCCCCAGAATCATGCG CTGCGCTCCGACAGCAGGCGCTGCCCTGGTGCTATGCGCGGCTACTGCGGGGCTTTTGAGCGCGCAAGGG CGCCCTGCACAGCCAGAGCCACCGCGCTTTGCATCCTGGGACGAGATGAACTTGCTGGCTCACGGGCTGC TACAGCTCGGCCATGGGCTGCGCGAACACGTGGAGCGCACCCGTGGGCAGCTGGGCGCGCTGGAGCGCCG CATGGCTGCCTGTGGTAACGCTTGTCAGGGGCCCAAGGGAAAAGATGCACCCTTCAAAGACTCCGAGGAT AGAGTCCCTGAAGGCCAGACTCCTGAGACTCTGCAGAGTTTGCAGACTCAGCTCAAGGCTCAAAACAGCA AGATCCAGCAATTGTTCCAGAAGGTGGCCCAGCAGCAGAGATACCTATCAAAGCAGAATCTGAGAATACA GAATCTTCAGAGCCAGATAGACCTCTTGGCCCCCACGCACCTAGACAATGGAGTAGACAAGACTTCGAGG GGAAAGAGGCTTCCCAAGATGACCCAGCTCATTGGCTTGACTCCCAACGCCACCCACTTACACAGGCCGC CCCGGGACTGCCAGGAACTCTTCCAAGAAGGGGAGAGGCACAGTGGACTTTTCCAGATCCAGCCTCTGGG GTCTCCACCATTTTTGGTCAACTGTGAGATGACTTCAGATGGAGGCTGGACAGTGATTCAGAGACGCCTG AACGGCTCTGTGGACTTCAACCAGTCCTGGGAAGCCTACAAGGATGGCTTCGGAGATCCCCAAGGCGAGT TCTGGCTGGGCCTGGAAAAGATGCACAGCATCACAGGGAACCGAGGAAGCCAATTGGCTGTGCAGCTCCA GGACTGGGATGGCAATGCCAAATTGCTCCAATTTCCCATCCATTTGGGGGGTGAGGACACAGCCTACAGC CTGCAGCTCACTGAGCCCACGGCCAATGAGCTGGGTGCCACCAATGTTTCCCCCAATGGCCTTTCCCTGC CCTTCTCTACTTGGGACCAAGACCATGACCTCCGTGGGGACCTTAACTGTGCCAAGAGCCTCTCTGGTGG CTGGTGGTTTGGTACCTGTAGCCATTCCAATCTCAATGGACAATACTTCCACTCTATCCCACGGCAACGG CAGGAGCGTAAAAAGGGTATCTTCTGGAAAACATGGAAGGGCCGCTACTATCCTCTGCAGGCTACCACCC TGCTGATCCAGCCCATGGAGGCTACAGCAGCCTCTTAGCCTCCTCACTGGAGCCTGGTTCCAGGCCTAAG AAGACAGTGACTTTGGTTGTGGCCCTGAGATTTGGCCATTCTCTGCTGGGGGCAGGAGCTCTAAGTAGGG CTATCTGCGTCTTGTGGACAAAGAAGAAGCCCGTAACTGGAGAGACTGGAGGACCCCTTTTCCGTGTTGG GGTCTGCAAGCATTGTTGTCTGAAACAGTCAGAGCAACAGGAAACAAATGGCCCAGATCCAGAAAACATG GGCTCGAGGGGCACTGAATATCACTTCTCGCCTACCAGAGAAGTTGGGGATGCAGAGGGACCACTACAGT CCAACTAGCTGGGCCCTTAATGGCGGACTCAGTCATATTGACTGACTGGAGACAGGGTGCCAGGAGCCCT GGATACACTCATGGTGCTGTTGTAGGTGCTGTGGATGCACAGGTGCTAACTGTGGTTCCCAGGCACAACT CACAGCATTCTTACAATAAAAACAACCTCAGAACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_020581
• Insert Size: 1233 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC006611, AAH06611
• RefSeq Size: 1869 bp
• RefSeq ORF: 1233 bp
• Locus ID: 57875
• UniProt ID: Q9Z1P8
• Cytogenetics: 17 B1
• Gene Summary: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:15837923, PubMed:17609370, PubMed:29899519). May also play a role in regulating glucose homeostasis and insulin sensitivity (PubMed:15837923, PubMed:29899519). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (PubMed:14583458, PubMed:17130448, PubMed:21832056). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (Probable).[UniProtKB/Swiss-Prot Function]