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Mvk (NM_023556) Mouse Untagged Clone

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SKU
MC200602
Mvk (untagged) - Mouse mevalonate kinase (Mvk), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $457.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Mvk
Synonyms 2310010A05Rik; AI256848; AI414037; MK
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC005606 sequence for NM_023556
GGAGAAGACCGGGAGCTGCGGCCCGGGTTTCAGCTCACTTGGGCGCTGGCCGGGGCAGAAGTCTCAGAAG CCATGTTGTCAGAAGCCCTGCTGGTGTCCGCCCCGGGGAAGGTCATCCTCCATGGAGAACACGCTGTGGT CCATGGCAAGGTCGCTCTGGCAGCGGCCTTGAACTTGAGAACTTTCCTCCTGCTGCGACCGCAGAGCAAT GGGAAAGTGAGCGTCAATTTACCCAACATCGGTATTAAGCAGGTGTGGGATGTGGGCATGCTTCAGCGAC TGGACACGAGCTTTCTTGAGCAAGGTGATGTCTCGGTACCCACCTTGGAGCAACTGGAGAAGCTAAAGAA GATGGGGGACCTCCCCAGAGACCGTGCAGGCAATGAAGGCATGGCTCTGCTTGCCTTTCTCTACCTGTAC CTGGCAATCTGCCGGAAGCAGAGGACACTCCCGAGCCTGGACATGGTGGTGTGGTCGGAACTTCCCCCCG GGGCAGGCTTGGGCTCCAGCGCCGCCTACTCTGTGTGTCTGGCAGCCGCCCTCCTGACTGCCTGTGAGGA GGTCTCCAACCCGCTCAAGGACGGGGTCTCCGTCAGCAGGTGGCCCGAGGAAGATCTGAAGTCAATCAAC AAGTGGGCCTTCGAAGGGGAGAGAGTGATCCATGGGAACCCTTCTGGTGTGGACAATGCCGTCAGCACCT GGGGCGGAGCCCTGCGCTTCCAGCAAGGGACGATGTCTTCCTTGAAGAGCCTCCCGTCTCTGCAGATCCT GCTCACCAACACCAAGGTCCCGCGGAGTACCAAGGCCCTTGTGGCTGCTGTCAGAAGCAGGCTGACCAAG TTCCCTGAGATTGTGGCCCCGCTGCTGACCTCCATTGACGCAATATCCCTGGAGTGTGAGCGCGTGCTAG GGGAGATGGTGGCAGCTCCAGTTCCGGAACAGTACCTCGTACTAGAAGAGCTGATAGACATGAACCAGCA CCATCTGAATGCTCTCGGGGTGGGCCACAACTCCCTGGACCAGCTCTGCCAAGTAACGGCAGCACACGGA CTGCACAGCAAGCTGACGGGCGCTGGCGGTGGCGGCTGTGGCATCACCCTCCTGAAGCCAGGTCTAGAGC AAGCCACAGTGGAGGCAGCCAAGCAGGCCCTGACCAGCTGCGGGTTTGACTGCTGGGAGACCAGCATCGG CGCACCCGGAGTTTCCACACACTCAGCTGCAGCTGTAGGGGACCCTGTCCGACAAGCCCTGGGCCTCTGA GACCACCCGACACACCATCCTACCAAGAAGCCTCTAAGTATCTGGGGCTGGAGTTGGCCTGCACCTTCTA GACTCTGACCTCATCCGTGTTCTGCCGTTTCTGAAGCCAGGCAGGGATTAGTTGTGGGGTCTTCTGAGAT GGCAGGCTGACACAGGAGGCCTTCGCCCTGGAGCTCCTATGGGCACATCGGCCTCACACAAACTCTCTGG CTCCTAGCCACGCACTCTTCTGTCCAGCCACGATGTCCCCTAAGGAACCACCTGGCCAGCAGCTCGTGGC TCCTGGCTCCTGGCTCTTGCCCTCTCTCGGAGATCATCAGCTGAGGCAAGGCATGCCGACTGCCTGTCTC CGTGTGGAAAAGCTGCTGTGGGGGAAATAAAAAGAAATAGTACAAACAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_023556
Insert Size 1188 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC005606, AAH05606
RefSeq Size 1712 bp
RefSeq ORF 1188 bp
Locus ID 17855
UniProt ID Q9R008
Cytogenetics 5 55.99 cM
Summary This gene encodes mevalonate kinase, a key enzyme involved in the biosynthesis of cholesterol and non-sterol isoprenes. The complete lack of encoded protein is lethal to mouse embryos. Mice lacking one allele of this gene exhibit increased levels of mevalonate in spleen, heart and kidney, as well as increased levels of serum immunoglobulins A and D. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
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Documents
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"NM_023556" in other vectors (4)
SKU Description Size Price
MG206185 Mvk (tGFP-tagged) - Mouse mevalonate kinase (Mvk) 10 ug
$657.00
MR206185 Mvk (Myc-DDK-tagged) - Mouse mevalonate kinase (Mvk) 10 ug
$289.00 $457.00
MR206185L3 Lenti ORF clone of Mvk (Myc-DDK-tagged) - Mouse mevalonate kinase (Mvk) 10 ug
$757.00
MR206185L4 Lenti ORF clone of Mvk (mGFP-tagged) - Mouse mevalonate kinase (Mvk) 10 ug
$757.00

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