Cd74 (BC003476) Mouse Untagged Clone

CAT#: MC200462

Cd74 (untagged) - Mouse CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cd74
• Synonyms: CLIP, DHLAG, HLADG, Ia-GAMMA
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC003476
  GCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCGCCTGTGGGAAAAA CTAGAGGCTAGAGCCATGGATGACCAACGCGACCTCATCTCTAACCATGAACAGTTGCCCATACTGGGCA ACCGCCCTAGAGAGCCAGAAAGGTGCAGCCGTGGAGCTCTGTACACCGGTGTCTCTGTCCTGGTGGCTCT GCTCTTGGCTGGGCAGGCCACCACTGCTTACTTCCTGTACCAGCAACAGGGCCGCCTAGATAAGCTGACC ATCACCTCCCAGAACCTGCAACTGGAGAGCCTTCGCATGAAGCTTCCGAAATCTGCCAAACCTGTGAGCC AGATGCGGATGGCTACTCCCTTGCTGATGCGTCCAATGTCCATGGATAACATGCTCCTTGGGCCTGTGAA GAACGTTACCAAGTACGGCAACATGACCCAGGACCATGTGATGCATCTGCTCACGAGGTCTGGACCCCTG GAGTACCCGCAGCTGAAGGGGACCTTCCCAGAGAATCTGAAGCATCTTAAGAACTCCATGGATGGCGTGA ACTGGAAGATCTTCGAGAGCTGGATGAAGCAGTGGCTCTTGTTTGAGATGAGCAAGAACTCCCTGGAGGA GAAGAAGCCCACCGAGGCTCCACCTAAAGTACTGACCAAGTGCCAGGAAGAAGTCAGCCACATCCCTGCC GTCTACCCGGGTGCGTTCCGTCCCAAGTGCGACGAGAACGGTAACTATTTGCCACTCCAGTGCCACGGGA GCACTGGCTACTGCTGGTGTGTGTTCCCCAACGGCACTGAGGTTCCTCACACCAAGAGCCGCGGGCGCCA TAACTGCAGTGAGCCACTGGACATGGAAGACCTATCTTCTGGCCTGGGAGTGACCAGGCAGGAACTGGGT CAAGTCACCCTGTGAAGACAGAGGCCAGCTCTGCACAGCAGCAGCGCCCCCTGCTCTCCTGTGCCTCAGC CCTTCTTATGTTCCCTGATGTCATACCCCACTTCCCGTCTCCCTGCACCCTGGGGCTTGAGACTGGTGTC TGTTTCATCGTCCCAGGACACGGCAAATGAAGTCAGAACAGAAGGAGGACGCTGGAGGGCCTTGCTGGCT ACCGCTATAAAGGCCCGCAGACAGGGACAAGGGATGCCCTACCCTTAACCTAGGCTGGACACATTTGCTG CCTTCTCCTCAAGGAAGAAGAACCCAAGCCCCTCCTCCCAGTAACCCCTCCTCACATCCTGCCACCCCCC CTCAAGCCCCACCCCCTTTCAGGTTCCTTGCTCAGCCAAGCTTGTCAGCAGCCTGTAGGATCATGGTTCA AGTGACAATAAAGGAAGAAAGTAGAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC003476
• Insert Size: 840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC003476, AAH03476
• RefSeq Size: 1375 bp
• RefSeq ORF: 840 bp
• Locus ID: 16149
• Cytogenetics: 18 34.41 cM
• Gene Summary: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.[UniProtKB/Swiss-Prot Function]