Dscr3 (NM_007834) Mouse Untagged Clone

CAT#: MC200359

Dscr3 (untagged) - Mouse Down syndrome critical region gene 3 (Dscr3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dscr3
• Synonyms: AW538125; Dcra
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC003740 sequence for NM_007834
  GCGGCCTTTGCGGATAATCTGAGATGGGGACCACTCTGGACATCAAGATTAAAAGAGCGAATAAAGTGTA TCACGCCGGGGAAATGCTCTCTGGTGTGGTGGTCATCTCTAGCAAGGACTCAGTCCAGCACCAGGGAGTC TCTTTGACAATGGAAGGGACTGTAAACCTCCAGCTCAGTGCCAAAAGTGTGGGTGTGTTCGAAGCCTTTT ACAACTCTGTGAAGCCGATCCAGATTATCAACAGCACCATAGACGTGCTGAAGCCAGGAAAGATTCCCAG TGGCAAGACTGAGGTCCCCTTTGAGTTCCCACTGCTTGTGAAAGGCAGCAAGGTCCTGTATGAGACTTAC CACGGCGTGTTTGTCAACATTCAGTACACACTGCGCTGTGACATGCGGCGGTCCCTGTTGGCCAAGGACC TGACCAAGACCTGTGAATTCATCGTTCACTCTGCCCCTCAGAAGGGGAAGTTGACCCCAAGTCCTGTTGA CTTCACGATCACTCCGGAAACCTTGCAGAACGTCAAAGAGAGAGCTTCACTTCCCAAATTCTTCATTAGA GGACATCTGAACTCCACTAACTGCGCTATCACGCAGCCCCTGACAGGAGAGCTGGTGGTGGAACACTCGG ATGCTGCTATCCGGAGCATAGAGCTTCAGTTGGTCCGGGTGGAGACCTGTGGGTGTGCAGAAGGCTATGC ACGAGATGCCACAGAGATTCAGAATATTCAAATCGCTGATGGGGACATTTGTAGAAACCTTTCTGTTCCC CTGTACATGGTCTTCCCCAGACTGTTCACCTGTCCAACACTGGAGACCACCAACTTCAAAGTGGAGTTTG AGGTCAATGTGGTGGTCCTCCTTCATGCTGACCACCTCATCACTGAGAACTTTCCGCTGAAGCTCTGTCG GACATAGTCCAGCTGCAGGAAGGGGAGAGCCAGAATGGCCATGTGGACATTGACCCAGTCATCTGCTCAC ATGGGGACGTCACACAGACCACCTGCTCACAGGCATCACATCAGCAGCATACATCTTCATGTCTTCTCAT GGCCTCAAAGCTTGTTCCCTGCAGGTGCCTTACCTCAGCCCTCACGTCTGGAATGCAACAGGATTTCTCC TGTGTGTTGCAAGATCACAGAAAGCGTTCCCAATGGCTCCAGATGTGCCTGTTTCTTCTTAGGTTCATTA AGCAGTGTGTCTGCACATTAAGATGGGCTGCCTAGTGAGATCATGGAGGCAGAAGAGAGCCCCCACCCCT CTATCTTGCCCAGACTCCTGACAGCAAAGAGTCAGCAACCAGCAAGCTCTCTGATTGAGTCTGTGATCCC CTCCAAGGAGTGACAGTGACTTCATCTGGGAATACGGAGTTTTCCCTTCTTGACATCTTGATAGTGTTTC ACTAAAGCCTCTAAATGTTTTAGGGCACTGGAAATAAAAACCAACAAATAGTCCTGGTTCTCACAGAGGG AGAATGGTGAACAGTGGCTGTCGCTGGAGTGTTTGTGTGTGTGGTACTGGCACACAGTTAATGCTGCCAT ATTCCCAGAATGTATTGAGAGACAAGGTGCTTGCATAAGGGGAAGAATGCACATGGACTACTGGTAAGTA CTAGGTTCTGAGTGACAGGACACCGTGCTGAGGAAGGGCAATGGCCTTGGCCTGTCCCTGACCCCCTGGG TCACATGGCTTTAGCCTCACACTGTAACTCATACTGTATGGAGGGTATGTTGCAATACTTTGCTTCCTTC GAATCTCGCTGTTGTTCTGTTGGTCCAGAGTTAATGAGCGCCCTGTACACCAGCTGGCCTGCCTTCACAG GTTCTGGGGGGCAGGCCGAGGCAAAGCAGGCCCGACTGGCAGCCTCCTGGCTGCACTCCCACTGTTCTGA ACAGCTGAGGGAACTGGGGCACTGCTGCTGGGGCCTCACCAGGGAAACTGAGAAGACTTAGCTGAGTCAC CTGACAGTGAGTTCCCAGAGAATGTACTTTTGCTTTGTCATACTTATCCTTGTTATATTTAAACAATCTA GTACCCAAAAAATGTGGGCCGTACTTTCTAGTGAGTCTAAGGAAAAGTCATCTTTGATTACATAATTTTT TTAATGAATAAAGAAAGCTAAACAAGAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_007834
• Insert Size: 894 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC003740, AAH03740
• RefSeq Size: 2141 bp
• RefSeq ORF: 894 bp
• Locus ID: 13185
• UniProt ID: O35075
• Cytogenetics: 16 C4
• Gene Summary: Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.[UniProtKB/Swiss-Prot Function]