Itm2b (NM_008410) Mouse Untagged Clone

CAT#: MC200158

Itm2b (untagged) - Mouse integral membrane protein 2B (Itm2b), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Itm2b
• Synonyms: AI256040; Bri; Bri2; Bricd2b; D14Sel6; E25BMM; imBRI2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004731 sequence for NM_008410
  CTCCGCTGCAGAGTCGTGCCCTGAGCTCGGCCGACAAGGCTGCCTTCGCAGCCGGGATCCTGCCAGCCGC GACCCCAGCCTTCGCCGTCGCCGCCTAGGGCGCCCCAGGCCGCACCATGGTGAAGGTGACGTTCAACTCG GCGCTGGCCCAGAAGGAGGCCAAGAAGGACGAGCCCAAGAGCAGCGAGGAGGCGCTCATCGTCCCTCCGG ATGCCGTGGCGGTGGATTGCAAGGACCCGGGTGACGTGGTTCCGGTTGGACAGAGGAGAGCGTGGTGTTG GTGCATGTGTTTCGGACTGGCCTTCATGCTTGCTGGCGTCATCCTCGGAGGGGCGTACCTGTACAAGTAT TTTGCTCTTCAGCCAGATGATGTGTACTATTGTGGACTAAAGTACATCAAAGATGACGTCATCCTGAACG AGCCTTCTGCGGATGCCCCAGCTGCTCGCTACCAGACAATTGAAGAGAACATTAAGATCTTTGAGGAAGA CGCAGTGGAATTCATCAGTGTGCCTGTACCAGAGTTTGCGGACAGCGATCCTGCCAACATTGTGCATGAC TTCAATAAGAAACTCACTGCTTATTTGGACCTTAACCTGGACAAGTGCTACGTGATTCCTCTGAACACTT CCATCGTTATGCCGCCCAAAAACCTGCTGGAGCTCCTTATTAACATTAAGGCCGGGACCTACCTGCCTCA GTCCTACCTTATCCATGAGCACATGGTGATCACCGACCGCATCGAGAACGTGGACAACCTGGGCTTCTTC ATCTACCGACTGTGTCACGACAAGGAGACCTACAAACTGCAGCGCCGGGAAACAATTAGAGGTATTCAGA AGCGGGAAGCCAGTAACTGTTTCACCATTCGGCATTTTGAGAACAAATTTGCTGTGGAGACTTTAATTTG TTCTTGAGAAGTCAAGAAAAAACGTGGGGAGGAATTCAATGCCACAGCATACCCTGCCCCTTTGTATTTT GTGCAGTGATTGTTTTTTAAAATCTTCTTTTCATGTAAGTAGCAAACAGGGCTTCACTGTCTCTTCATCT CAATAACTCAATTAAAAACCATTATCTTAAAAAAAGAAAACAAAACCTTTCTTTTTTCTAAGTGTGGTGT CTTTGATGTTTGAATTAGCAAATGTGCAGGTTCCTAGATAAGATTCGCTTCTCCTTAGAGCTTACCTACT AGGAAGAATCTAAATTGCTTGGAAATCACTAATCTGGATTTTTGTGTTAATTCTGCACTTCCATGAGGGA AAGATGCCTAAAGAATAGTCATTCGCATATGTTAAAGGGACCACCGTGACTTGCTTGTAGACGCTAGCCC TGCTACCTAGTCTGTTAGCATTTGAAGTCACCGTCTCTACTACTTTAATTGAAATGTGCCCTATCTTCAA TGTTGCTTTAACTACTTTAGAGGGTTTCAGCCCTGATGTTTTAATATCCTAGGCCTCTGCTGTAATAAGA TTTTAGACAAATGTTTGGAATTTAAGAAGCAACTCATGTTACTAATTTGTATAGCCCATATCTGTGGAAT GGAATATAAATATCACAAAGCCAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_008410
• Insert Size: 801 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004731, AAH04731
• RefSeq Size: 1577 bp
• RefSeq ORF: 801 bp
• Locus ID: 16432
• UniProt ID: O89051
• Cytogenetics: 14 38.88 cM
• Gene Summary: Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity).[UniProtKB/Swiss-Prot Function]