Angiotensin II Type 1 Receptor (AGTR1) (NM_009585) Human 3' UTR Clone
CAT#: SC210894
3' UTR clone of angiotensin II receptor type 1 (AGTR1) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | AGTR1 |
Synonyms | AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R |
ACCN | NM_009585 |
Insert Size | 918 bp |
Sequence Data |
>SC210894 3’UTR clone of NM_009585
The sequence shown below is from the reference sequence of NM_009585. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGCCTGCACCATGTTTTGAGGTTGAGTGACATGTTCGAAACCTGTCCATAAAGTAATTTTGTGAAAGA AGGAGCAAGAGAACATTCCTCTGCAGCACTTCACTACCAAATGAGCATTAGCTACTTTTCAGAATTGAA GGAGAAAATGCATTATGTGGACTGAACCGACTTTTCTAAAGCTCTGAACAAAAGCTTTTCTTTCCTTTT GCAACAAGACAAAGCAAAGCCACATTTTGCATTAGACAGATGACGGCTGCTCGAAGAACAATGTCAGAA ACTCGATGAATGTGTTGATTTGAGAAATTTTACTGACAGAAATGCAATCTCCCTAGCCTGCTTTTGTCC TGTTATTTTTTATTTCCACATAAAGGTATTTAGAATATATTAAATCGTTAGAGGAGCAACAGGAGATGA GAGTTCCAGATTGTTCTGTCCAGTTTCCAAAGGGCAGTAAAGTTTTCGTGCCGGTTTTCAGCTATTAGC AACTGTGCTACACTTGCACCTGGTACTGCACATTTTGTACAAAGATATGCTAAGCAGTAGTCGTCAAGT TGCAGATCTTTTTGTGAAATTCAACCTGTGTCTTATAGGTTTCCACTGCCAAAACAATGCCCGTAAGAT GGCTTATTTGTATAATGGTGTTACTAAAGTCACATATAAAAGTTAAACTACTTGTAAAGGTGCTGCACT GGTCCCAAGTAGTAGTGTCTTCCTAGTATATTAGTTTGATTTAATATCTGAGAAGTGTATATAGTTTGT GGTAAAAAGATTATATATCATAAAGTATGCCTTCCTGTTTAAAAAAAGTATATATTCTACACATATATG TATATGTATATCTATATCTCTAAACTGCTGTTAATTGATTAAAATCTGGCAAAGTTATATTTACTTTAA AATAAAATAATTTTATTGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_009585.4 |
Summary | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020] |
Locus ID | 185 |
MW | 35.9 |
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