NRG1 (NM_013956) Human 3' UTR Clone

CAT#: SC208368

3' UTR clone of neuregulin 1 (NRG1) transcript variant HRG-beta1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: NRG1
• Synonyms: ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF
• ACCN: NM_013956
• Insert Size: 2000 bp
• Sequence Data:
  Insert Sequence

  >SC208368 3’UTR clone of NM_013956
  The sequence shown below is from the reference sequence of NM_013956. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  ATTGCTAACCAAGACCCTATTGCTGTATAAAACCTAAATAAACACATAGATTCACCTGTAAAACTTTAT
  TTTATATAATAAAGTATTCCACCTTAAATTAAACAATTTATTTTATTTTAGCAGTTCTGCAAATAGAAA
  ACAGGAAAAAAACTTTTATAAATTAAATATATGTATGTAAAAATGTGTTATGTGCCATATGTAGCAATT
  TTTTACAGTATTTCAAAACGAGAAAGATATCAATGGTGCCTTTATGTTATGTTATGTCGAGAGCAAGTT
  TTGTACAGTTACAGTGATTGCTTTTCCACAGTATTTCTGCAAAACCTCTCATAGATTCAGTTTTTGCTG
  GCTTCTTGTGCATTGCATTATGATGTTGACTGGATGTATGATTTGCAAGACTTGCAACTGTCCCTCTGT
  TTGCTTGTAGTAGCACCCGATCAGTATGTCTTGTAATGGCACATCCATCCAGATATGCCTCTCTTGTGT
  ATGAAGTTTTCTTTGCTTTCAGAATATGAAATGAGTTGTGTCTACTCTGCCAGCCAAAGGTTTGCCTCA
  TTGGGCTCTGAGATAATAGTAGATCCAACAGCATGCTACTATTAAATACAGCAAGAAACTGCATTAAGT
  AATGTTAAATATTAGGAAGAAAGTAATACTGTGATTTAAAAAAAACTATATTATTAATCAGAAGACAGC
  TTGCTCTTACTAAAAGGAGCTCTCATTTACTTTATTTGATTTTATTTTTCTTGACAAAAAGCAACAGTT
  TTAGGGATAGCTTAGAAAATGGGTTCTGGCTTGCTATCAGGGTAAATCTAACACCTTACAAGAGGACTG
  AGTGTCACTTTCTCTCTGGGGGAATGATCCAGCAGCTTATCTAGTTGACAATCAAAACACGGCTGATAA
  AGGTGCAATCATTTCTGACATGTATTTTTCACTGATTTTGAAGCTAGTGATTGGTTGTGTCTTCTTGGC
  TCAAAAAGAAGCATATTACGGCACAAAAAGCCCAGCCCAGACAGCACATGCAGCATTTTGTCTGAAATA
  CTTCTAGAGTCAAACGTGCCTGCTGTACATAGCGATGACTTGTCATCATAGGGAAGTATTTCCATCGTA
  GAGTGTTCAGAAGGAGTGACTGTATAGGTGGAGAGAAGCTTAGTGACTCCGTTGAAATTTTAAAATGTG
  GATGACCACCCCTTTCTCCCCCTTATTTTTCTTTTATCTTTCCATGTTGCCTTGATCAGGTCATAACTA
  TGCATGAACATTTTTTATCAGGAATGGCCGATGTGTATGTGATTTGTAATCACAAGTAATGATTCATCA
  GGAAATGTCAATCCTGTTGGAAAGATTGCACCTTTACTTGCAGAAGTGACCCCCACCTGTGTCCTGACC
  TCTCCATTTACAGGCTCTCTCACCCATTTCCCCCACCTCCTTTAATTTTTGCTTTACTGTCATAAAGTA
  GGACTAAGATTGGTCTAAGCATTGCATGTTCTTTTGTGATGGTAAATCCAAAGGAAGGCCTATAAGTAT
  TAACATTTGAAATAACTGCTAATTCAGGAAAATGGAAGAAAAAAAATTATTTGAAACACAGAACCCATT
  TCATGGCCTGCCTGATATCTGTGAAATCAGGGCTGGAGCTTTACTTAGGATTCACATGGCCTCCTAGGA
  ACCATGGGACAAATGGGAAACAGGTTATCGGGGGATTCATGAAGTCAGTGAGAGTAATTGCTTCTTTTT
  TGCGGGTGAACTGAATGTATTTCTTCACCAAATCTTGATGTTAACAATTAAAAAGAAGAAATGACATGC
  AAGTAGGTCTTAGCAGAAAAATGCAGGCTGGGCATGAGTCATGTTGTTACCCTCCCACATGCTCCTACA
  ATCCACAGAGATGCCTGTCTGCAGGTTCTTGAAGTTATTGTTAGTATTTGGTATCTCAAATTTTTCGTC
  ACTGTTCACATGCCACTTTCTCTGTGCACAGTGGTATCCTCATTTGCTTTTTAACCTACACTGAGGAG
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_013956.5
• Summary: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
• Locus ID: 3084
• MW: 75.7