PANK2 (NM_153640) Human 3' UTR Clone
SKU
SC207513
3' UTR clone of pantothenate kinase 2 (PANK2) transcript variant 2 for miRNA target validation
$683.00
4 Weeks*
Specifications
| Product Data | |
| Vector | pMirTarget |
|---|---|
| Species | Human |
| Transfection Reporter | RFP |
| Assay Reporter | Luciferase |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Target Symbol | PANK2 |
| Synonyms | C20orf48; HARP; HSS; NBIA1; PKAN |
| ACCN | NM_153640 |
| Insert Size | 2000 bp |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
| Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_153640.4 |
| Locus ID | 80025 |
| Summary | This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. provided by RefSeq, Jul 2008 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.