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BCAR1 (NM_014567) Human 3' UTR Clone

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SKU
SC206721
3' UTR clone of breast cancer anti-estrogen resistance 1 (BCAR1) for miRNA target validation
  $683.00
4 Weeks*
Size
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Vector pMirTarget
Species Human
Transfection Reporter RFP
Assay Reporter Luciferase
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Target Symbol BCAR1
Synonyms CAS; CAS1; CASS1; CRKAS; P130Cas
ACCN NM_014567
Insert Size 1360 bp
Sequence Data
Insert Sequence
>SC206721 3’UTR clone of NM_014567
The sequence shown below is from the reference sequence of NM_014567. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CGCGTCCTAGGCCAGCTGGCAGCCGCCTGAGGGTGGTGACCCCAGGAGGGAGGCAGGGGAGGGGTGCGG
CGGTCCCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAGGGACAGGACCCCAGCTC
TGCGTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGCAGGGTGTGGGGCC
ATGCCTCCTCAGGAGCCGAAGCCCAGGGGCCGGCCAGTGGCCTTCCCCAGCATGCACCACGGGCCCGGG
TTGGGTCACCAGACGGGGCTGGAGTGTGAGGGTCCTGCAGCCTGCAGGACCTCGTGCCACCCCGAGGGC
TGAGCCTGGTCCCACGAGGGTGCCGTGTCCCCTGACAGGGCCAGTGCAGTTTGGTGTGTCCTCCGCCTT
ACCAGGAGAAGAACCTGAAGAACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCCAT
TTAAATAAAGTTTTTAAAAGGAAGAGCAGCTGCCTGAGGGTGGCAGATGAGAGCAGCCCGGGGTGGGTG
ACGGTTCTGGGGAAGGCACCCGGGGGCAAGGGCCATGCGTGGCATCTCCCGGGAGGGCAGAGGAGGAGT
GGGTCTCTCTAGAAGAAAACCAAGGAACGCCGAGGCTGGGTGTCTCCTGGAGGCGGGGTGAGGCCTGCA
GCTGGCCACAAGGCCCTGGGAGCCAGGGCAGAGCCTGGGCCCAAGAAAGGGGGCAGTTTCAGAGCTGCA
GGGTCTGGGGCCCAGAAAGCACAGCCTGGGCATGGCCCCTGCAACCCTAGGGAGCTGCCACAGTGAGCA
CCTGCCCATGCCCACAGCTGGCATCTGGAGTGAGGGCAGATTGGGGCAGGAACAGCTGCACAAGGGGAC
GGGTTCCTGTGAGCCGAGGGCACCGCTGGGGGCTGCATCCAGAGCTCTGCTTAAAAGAATCTCATCCCA
GCCTGCGGAACTCCCGAAGTGCACATGGAATTATACCTGGACCTGGCATCTGAGTTGGGAGGGAGGGGC
TTGGAGAAGACCCTTGCCCTGGGCAAGTGTGTCCCCCTTCGTGGCTCCCCCACCCAGCAGCCCGCAGCC
CAGATGGAAGCTTCAGGGTGCTTGGAACCCCTGGTGCTGCTCCCAGCCCTGACCGTTCTGCATATGAAC
ATGGGCCTTGGTTTCCCCATCTGTATGAAGAAGGGAGTAGGGCTGGGTGATTCGCAAGCCCTCCTGATC
TTACCTCTACAGAGGTTGTCCCCGTGACAGCATCTGTCCCCCCACCTCAGCCACATCATGCTCAGCCCA
CCTGCCTTGGTGAGGACACAGAGGTAAAGGTGTATGCAGTTGCTCTCAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI |
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014567.5
Locus ID 9564
Summary The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
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