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DMGDH (NM_013391) Human 3' UTR Clone

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SKU
SC206697
3' UTR clone of dimethylglycine dehydrogenase (DMGDH) nuclear gene encoding mitochondrial protein for miRNA target validation
  $683.00
4 Weeks*
Size
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Vector pMirTarget
Species Human
Transfection Reporter RFP
Assay Reporter Luciferase
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Target Symbol DMGDH
Synonyms DMGDHD; ME2GLYDH
ACCN NM_013391
Insert Size 548 bp
Sequence Data
Insert Sequence
>SC206697 3’UTR clone of NM_013391
The sequence shown below is from the reference sequence of NM_013391. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CAGAAAAAAGGTGGAAAGGACAAAACTTGAAAAAAGACCTTCAGCAGTCAACTGAATTAGAGTTGCTAA
TGACTGTCCTTGAAATTATTATAACTGGCTCCCAGGGGAATAGAGGAAACCAGGAATTCATTTCAAAAT
CATCAAAGTCTAAATTTAGAATCTTAATGAAACCTTTCTGTTAAGTGTTTTCTAAGCAAGACAGAATAA
TAGATAAATGATTTACATTGTTCTTTTAAATGAAGAAATTTGAAATGAATGTTTTTTTATTTACCCCAC
ATTACCCAATCAGTAAAACATTTAGGTGTTTGCTAATATACACAATCATTACTATAACCTAATTAAGGG
ACATTTTATAATTTTAGTAACAAATGCATTCGGTTCTTGACAGCTGAAAACAAATTAATAAATTATCTT
TTACATAAAAACATGTACAATATTGTTTATGGATTTACTTCTTTGAGAAATCTTTCCTTAGATGAATAA
ATGAAAGTTTTAATTTTTCATGATATATCTGTGATGAAAATAGTAAAACTTAACATTGACATATA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI |
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_013391.3
Locus ID 29958
Summary This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.