Human TGF beta 2 (TGFB2) ELISA KIT (96 T)

CAT#: EA800102

Human TGF-β-2 ELISA KIT

Product Images

Representative standard curve for TGF-β-2 ELISA

Specifications

Product Data

• Format: 96-well strip plate
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: 4 hours
• Signal: Colorimetric
• Curve Range: 35-2200pg/ml
• Sample Type: Serum, plasma, Cell culture supernatant
• Sample Volume: 100 uL
• Specificity: This assay recognizes both natural and recombinant human TGF-β2.
• Sensitivity: 18 pg/mL
• Reactivities: Human
• Interference: No significant interference observed with available related molecules.
• Components:
  • Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate
  • Standard - lyophilized,2200 pg/ml upon reconstitution,3 vials
  • Concentrated Biotin-Conjugated antibody,1 vial
  • Concentrated Streptavidin-HRP,1 vial
  • 20 x Assay Buffer,1 bottle
  • Reagent Diluent,1 bottle
  • 20 x PBS,1 bottle
  • 1 M HCl,1 bottle
  • Neutralization Buffer,1 bottle
  • 20 x Wash Buffer Concentrate,1 bottle
  • Substrate Solution,1 bottle
  • Stop Solution,1 bottle
  • Plate Cover Seals,4 pieces
• Background: Vascular endothelial growth factor (TGF-β2)TGF-β2 (Transforming growth factor-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGFB1, TGFB2, and TGFB3 all function through the same receptor signaling systems. They are members of the large TGF-β superfamily. TGF-β proteins are highly pleiotropic cytokines that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β activation from latency is controlled both spatially and temporally, by multiple pathways that include actions of proteases such as plasmin and MMP9, and/or by thrombospondin 1 or selected integrins. The active form of TGF-β2 is a disulfide-linked homodimer which is generated by activation of the latent TGF-β2 complex. TGF-βs are multifunctional cytokines that activate or repress multiple genes in a wide variety of cell types. Depending on the cell context, TGF-β can control many cellular processes including growth, morphogenesis, and apoptosis.
• Gene Symbol: TGFB2
• Gene ID: 7042