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Human CD1C ELISA Kit (1 x 96 wells)

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SKU
EA200073
Human CD1C ELISA Kit (1 x 96 wells)
  $510.00
4 Weeks*
Specifications
Specifications
Product Data
Species Human
Format 8x12 divisible strips
Assay Type microplate ELISA
Assay Length 3.5 hours incubations; 0.5 hour washing and analyzing samples
Signal Colorimetric
Curve Range 0.156-10ng/mL
Sample Type Human serum, plasma, cell lysates and other biological fluids.
Sample Volume 100µl
Specificity This kit is used for quantitative detection of CD1C
Sensitivity 84pg/mL
Reactivity Human
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • CD1C Antibody Coated 96-well Plate in foil pouch with desiccant | 1 plate
  • CD1C Standard Protein | 0.1 mL
  • CD1C Detection Antibody | 14 mL
  • 1x SA-HRP Conjugate | 14 mL
  • Assay Buffer | 40 mL
  • Sample Diluent | 30 mL
  • Wash Buffer Concentrate 20X | 60 mL
  • TMB Substrate | 14 mL
  • Stop Solution | 14 mL
Background CD1C, also called BDCA-1, plays roles in adaptive immunity, tissue homeostasis, and autoimmune diseases. CD1C is a member of the CD1 family of proteins that are structurally related to MHC class I proteins. Human CD1 family proteins (CD1A, CD1B, CD1C, CD1D, and CD1E) have different structural frameworks in their ligand-binding pockets, which may result in their different preference for bound lipids. In addition, CD1 isotypes distribute differently in the cellular endomembrane system. CD1C is expressed on the surface of antigen-presenting cells, including dendritic cells, B cells, and Langerhans cells. Like MHC class I molecules (MHC-I), CD1 proteins form heterodimers with β2-macroglobulin (B2M) and present lipid antigens on the cell surface to interact with T cells. Diseases associated with CD1C include Histiocytosis and Follicular Dendritic Cell Sarcoma.
Gene Symbol CD1C
Locus ID 911
Standard Curve
Shipping Blue Ice
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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