Human Angiotensin Converting Enzyme 2 (ACE2) ELISA KIT (1 x 96 wells)

SKU EA200003

Human Angiotensin Converting Enzyme 2 (ACE2) ELISA KIT (1 x 96 wells)

Product Data

• Format: 8x12 divisible strips
• Assay Type: Sandwich
• Assay Length: 4 hours incubations; 1 hour washing and analyzing samples
• Signal: Colorimetric
• Curve Range: 78pg/ml-5000pg/ml
• Sample Type: Cell culture supernates, serum and plasma (heparin).
• Sample Volume: 100µl
• Specificity: This kit is used for quantitative detection of Human ACE2
• Sensitivity: 19.88pg/ml
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Interference: No significant interference observed with available related molecules.
• Components:
  • ACE2 Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate
  • Recombinant Human ACE2 Standard (250ng/ml)| 0.1 mL
  • 100x Biotinylated HumanACE2 Detection Antibody| 0.12 mL
  • Assay Buffer| 30 mL
  • Sample Diluent|12 mL
  • 100x Peroxidase Conjugate| 0.12 mL
  • Wash Buffer Concentrate 20X| 60 mL
  • Substrate|12 mL
  • Stop Solution|12 mL
• Background: Angiotensin I-converting enzyme 2 (ACE2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2.
• Gene Symbol: ACE2
• Locus ID: 59272