Human Granzyme A (GZMA) ELISA KIT (1 x 96 wells)
CAT#: EA102247
For quantitative detection of human Granzyme A in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for human Granzyme A |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 15.6pg/ml-1000pg/ml |
Specificity | This kit is used for quantitative detection of human Granzyme A |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface "nonself" antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. GZMA induces caspase-independent apoptosis in a characteristic manner, except it causes a distinctive form of DNA damage: single-stranded DNA nicking. A target of GZMA is the SET complex, including HMGB2 and ANP32A. |
Gene Symbol | GZMA |
Gene ID | 3001 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.