Human TNF alpha ELISpot Set, 15 x 96-well (plates not included)

CAT#: EA101491

Human TNF alpha ELISpot Set, 15 x 96-well (plates not included)

Specifications

Product Data

• Format: 15 x 96-well (plates not included)
• Assay Type: Enzyme-Linked ImmunoSpot (ELISpot)
• Assay Length: 3h after cell stimulation
• Signal: Colorimetric
• Specificity: Recognizes natural human TNF-a
• Cross Reactivity: No cross reactivity with other human cytokines. Cross reacivity with macac TNF-a. No interference with TNFR I and TNFR II.
• Components: ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, and blocking reagent.
• Background: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
• Gene Symbol: TNF
• Gene ID: 7124