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CD45 (PTPRC) Mouse Monoclonal Antibody [Clone ID: UMAB291]

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SKU
UM800180
CD45(PTPRC) mouse monoclonal antibody, clone UMAB291
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated

Hu Tonsil, IHC, DAB Mouse w/ PV, 1:4000 H1-20

  $610.00
In Stock*
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View other "CD45 or NM_002838" antibodies

Specifications
Specifications
Product Data
Clone Name UMAB291
Application IHC
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 221-396 of human CD45 (NP_002829) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Shipping Blue Ice
Predicted Protein Size 147.1 kDa
Gene Name protein tyrosine phosphatase receptor type C
Database Link
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. provided by RefSeq, Jun 2012
Synonyms B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Reference Data
Protein Categories ADC Targets, CD Markers, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway
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Resources
Other "UMAB291" antibodies (2)
SKU Description Size Price
UM800180CF Carrier-free (BSA/glycerol-free) CD45(PTPRC) mouse monoclonal antibody, clone UMAB291 100 ug
$680.00
UM870180 CD45(PTPRC) mouse monoclonal antibody, clone UMAB291 30 ul
$224.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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