MLH1 Mouse Monoclonal Antibody [Clone ID: UMAB191]
USD 436.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Clone Name | UMAB191 |
Applications | IF, IHC, WB |
Recommended Dilution | IHC 1:200 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 299-527 of human MLH1(NP_000240) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 84.4 kDa |
Gene Name | Homo sapiens mutL homolog 1 (MLH1), transcript variant 1, mRNA. |
Database Link | |
Background | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009] |
Synonyms | COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM800083CF | Carrier-free (BSA/glycerol-free) MLH1 mouse monoclonal antibody,clone UMAB191 |
USD 657.00 |
|
UM870083 | MLH1 mouse monoclonal antibody,clone UMAB191 |
USD 224.00 |
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