MET Mouse Monoclonal Antibody [Clone ID: UMAB190]

CAT#: UM800082

MET mouse monoclonal antibody,clone UMAB190


 Product Datasheet for 'UM800082'

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USD 468.00


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name UMAB190
Applications WB, IHC, IF
Recommend Dilution IHC 1:150,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 570-885 of human MET(NP_000236) produced in E.coli.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 153 kDa
Gene Name Homo sapiens MET proto-oncogene, receptor tyrosine kinase (MET), transcript variant 2
Background The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
Synonyms AUTS9; c-Met; DFNB97; HGFR; RCCP2
Reference Data
Protein Families Protein Kinase, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Axon guidance, Focal adhesion, Adherens junction, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, Colorectal cancer, Renal cell carcinoma, Melanoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.