MET Mouse Monoclonal Antibody [Clone ID: UMAB190]
Specifications
| Product Data | |
| Clone Name | UMAB190 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 570-885 of human MET(NP_000236) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 153 kDa |
| Gene Name | MET proto-oncogene, receptor tyrosine kinase |
| Database Link | |
| Background | The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008) |
| Synonyms | AUTS9; c-Met; DFNB97; HGFR; RCCP2 |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Bladder, Cancer: Gastrointestinal, Cancer: Lung, Cancer: Sarcoma, CAR-T Targets, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Adherens junction, Axon guidance, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Focal adhesion, Melanoma, Pathways in cancer, Renal cell carcinoma |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "UMAB190" antibodies (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| UM800082CF | Carrier-free (BSA/glycerol-free) MET mouse monoclonal antibody,clone UMAB190 | 100 ug |
$680.00
|
|
| UM870082 | MET mouse monoclonal antibody,clone UMAB190 | 30 ul |
$224.00
|
|
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