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CD5 Mouse Monoclonal Antibody [Clone ID: UMAB9]

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SKU
UM570009
CD5 mouse monoclonal antibody, clone UMAB9
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $224.00
In Stock*
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Specifications
Specifications
Product Data
Clone Name UMAB9
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500, IHC 1:100, IF 1:100, FLOW 1:100, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD5 (NP_055022) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 54.4 kDa
Gene Name CD5 molecule
Database Link
Background CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of theirB-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 is a good immunohistochemical marker for T-cells. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukaemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukaemia, while relatively rare, is associated with a poor prognosis.
Synonyms LEU1; T1
Reference Data
Protein Categories CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage
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Other "UMAB9" antibodies (2)
SKU Description Size Price
UM500009 CD5 mouse monoclonal antibody, clone UMAB9 100 ul
$610.00
UM500009CF Carrier-free (BSA/glycerol-free) CD5 mouse monoclonal antibody, clone UMAB9 100 ug
$680.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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