CD44 Mouse Monoclonal Antibody [Clone ID: UMAB134]
CD44 mouse monoclonal antibody,clone UMAB134
Product Datasheet for 'UM500099'
|Applications||IF, IHC, WB|
|Recommend Dilution||IHC 1:500|
|Immunogen||Full length human recombinant protein of human CD44(NP_000601) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Concentration||0.5~1.0 mg/ml (Lot Dependent)|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Gene Name||Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1, mRNA.|
|Background||The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]|
|Synonyms||CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1|
|Protein Families||Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane|
|Protein Pathways||ECM-receptor interaction, Hematopoietic cell lineage|
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