IDO1 Mouse Monoclonal Antibody [Clone ID: UMAB126]

CAT#: UM500091

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IDO1 mouse monoclonal antibody,clone UMAB126



  View other "UMAB126" antibodies (2)

USD 549.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name UMAB126
Applications 10k-ChIP, IF, IHC, WB
Recommended Dilution IHC 1:100~200
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IDO1(NP_002155) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 45.1 kDa
Gene Name Homo sapiens indoleamine 2,3-dioxygenase 1 (IDO1), mRNA.
Background This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. [provided by RefSeq, Feb 2011]
Synonyms IDO; IDO-1; INDO
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Tryptophan metabolism

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