IDO1 Mouse Monoclonal Antibody [Clone ID: UMAB126]
Specifications
| Product Data | |
| Clone Name | UMAB126 |
|---|---|
| Application | 10k-ChIP, IF, IHC, WB |
| Recommended Dilution | IHC 1:100~200 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human IDO1(NP_002155) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 45.1 kDa |
| Gene Name | indoleamine 2,3-dioxygenase 1 |
| Database Link | |
| Background | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. provided by RefSeq, Feb 2011 |
| Synonyms | IDO; IDO-1; INDO |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Tryptophan metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "UMAB126" antibodies (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| UM500091CF | Carrier-free (BSA/glycerol-free) IDO1 mouse monoclonal antibody,clone UMAB126 | 100 ug |
$680.00
|
|
| UM570091 | IDO1 mouse monoclonal antibody,clone UMAB126 | 30 ul |
$224.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
