PBX1 Mouse Monoclonal Antibody [Clone ID: UMAB110]

CAT#: UM500077

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PBX1 mouse monoclonal antibody,clone UMAB110



  View other "UMAB110" antibodies (2)

USD 564.00


Availability*
In Stock

Size
    • 100 ul


Other products for "PBX1"

Specifications

Product Data
Clone Name UMAB110
Applications 10k-ChIP, IF, IHC
Recommended Dilution IHC 1:100~200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46.4 kDa
Gene Name Homo sapiens PBX homeobox 1 (PBX1), transcript variant 1, mRNA.
Background This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar
Synonyms CAKUHED; DKFZp686B09108; MGC126627
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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