alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: UMAB66]

CAT#: UM500056

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AFP mouse monoclonal antibody, clone UMAB66



USD 527.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name UMAB66
Applications 10k-ChIP, IF, IHC, WB
Recommended Dilution IHC 1:100, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human AFP (NP_001125) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 66.3 kDa
Gene Name Homo sapiens alpha fetoprotein (AFP), transcript variant 1, mRNA.
Background This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
Synonyms AFPD; FETA; HPAFP
Reference Data
Protein Families Druggable Genome, Secreted Protein
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