UBE2L3 Rabbit Polyclonal Antibody

CAT#: TA890154S

Rabbit Polyclonal anti-UBE2L3 Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Cat# PS100001, Left lane) or pCMV6-ENTRY UBE2L3 (Cat# RC208780, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBE2L3 antibody (Cat# TA890154). Positive lysates LY401144 (100ug) and LC401144 (20ug) can be purchased separately from OriGene.

• 

  Western blot analysis of extracts (35ug) from different cell lines and tissues by using anti-UBE2L3 rabbit polyclonal antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~2000
• Reactivities: Human, Rat, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human UBE2L3
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1.45 mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 17.7 kDa
• Gene Name: ubiquitin conjugating enzyme E2 L3
• Database Link:
  NP_003338
  Entrez Gene 22195 MouseEntrez Gene 363836 RatEntrez Gene 7332 Human
  UniProt ID P68036
• Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
• Synonyms: E2-F1; L-UBC; UBCH7; UbcM4

Reference Data

• Protein Pathways: Parkinson's disease, Ubiquitin mediated proteolysis