IL6 Mouse Monoclonal Antibody [Clone ID: OTI8C8]

CAT#: TA813829S

IL-6 mouse monoclonal antibody, clone OTI8C8

Specifications

Product Data

• Clone Name: OTI10A1 OTI10C5 OTI12C12 OTI12C5 OTI12E5 OTI1A6 OTI1D11 OTI1D2 OTI1D9 OTI1E9 OTI2A6 OTI2B10 OTI2B12 OTI2B3 OTI2B7 OTI2B8 OTI2C11 OTI2E9 OTI2G10 OTI2G5 OTI3A3A8 OTI3A3B1 OTI3A4 OTI3B3 OTI3E5 OTI3F3 OTI4C4 OTI5G7 OTI6D1 OTI6D3 OTI7A4 OTI7D1 OTI7D8 OTI8C8
• Applications: ELISA
• Recommended Dilution: ELISA 1:5000-10000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human IL-6 (NP_000591) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 23.7 kDa
• Gene Name: interleukin 6
• Database Link:
  NP_000591
  Entrez Gene 3569 Human
  UniProt ID P05231
• Background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
• Synonyms: BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway