IL28 Receptor alpha (IFNLR1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F5]

CAT#: TA812609AM

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IFNLR1 mouse monoclonal antibody,clone OTI3F5, Biotinylated



USD 462.00


Availability*
2 Weeks

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI3F5
Applications IHC, WB
Recommended Dilution WB 1:500, IHC 1:500
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 21-228 of human IFNLR1 (NP_734464) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name interferon lambda receptor 1
Background The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
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