MASP2 Mouse Monoclonal Antibody [Clone ID: OTI4D4]

CAT#: TA812529S

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MASP2 mouse monoclonal antibody,clone OTI4D4



  View other "OTI4D4" antibodies (2)

USD 169.00


Availability*
2 Days

Size
    • 30 ul


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Specifications

Product Data
Clone Name OTI4D4
Applications WB
Recommended Dilution WB 1:500
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 445-686 of human MASP2 (NP_006601) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 75.69 kDa
Gene Name mannan binding lectin serine peptidase 2
Background This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Synonyms MAP19; MASP-2; MASP1P1; sMAP
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades

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