LDL Receptor (LDLR) Mouse Monoclonal Antibody [Clone ID: OTI8D12]
CAT#: TA812508S
LDLR mouse monoclonal antibody,clone OTI8D12
Size: 100 ul
View other "OTI8D12" antibodies (4)
Special Offer: Get this product for $99/€99. Use code: "Truesample".
USD 200.00
Specifications
Product Data | |
Clone Name | OTI8D12 |
Applications | FC, WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human LDLR (NP_000518) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 95.38 kDa |
Gene Name | low density lipoprotein receptor |
Database Link | |
Background | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010] |
Synonyms | FH; FHC; FHCL1; LDLCQ2 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Endocytosis |
Documents
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FAQs |
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Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF812508 | Carrier-free (BSA/glycerol-free) LDLR mouse monoclonal antibody,clone OTI8D12 |
USD 600.00 |
|
TA812508 | LDLR mouse monoclonal antibody,clone OTI8D12 |
USD 447.00 |
|
TA812508AM | LDLR mouse monoclonal antibody,clone OTI8D12, Biotinylated |
USD 509.00 |
|
TA812508BM | LDLR mouse monoclonal antibody,clone OTI8D12, HRP conjugated |
USD 509.00 |
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