NCF4 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4B5]

CAT#: TA809135BM

NCF4 mouse monoclonal antibody, clone OTI4B5 (formerly 4B5), HRP conjugated

Conjugation: Unconjugated Biotin HRP


  View other "OTI4B5" antibodies (4)

USD 509.00

2 Weeks*

Size
    • 100 ul

Frequently bought together (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00


Recombinant protein of human neutrophil cytosolic factor 4, 40kDa (NCF4), transcript variant 1, 20 µg
    • 20 ug

USD 867.00


Transient overexpression lysate of neutrophil cytosolic factor 4, 40kDa (NCF4), transcript variant 2
    • 100 ug

USD 436.00

Other products for "NCF4"

Specifications

Product Data
Clone Name OTI4B5
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NCF4 (NP_000622) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 38.9 kDa
Gene Name neutrophil cytosolic factor 4
Background The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Synonyms NCF; P40PHOX; SH3PXD4
Reference Data
Protein Pathways Leukocyte transendothelial migration

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.