EXOSC1 Mouse Monoclonal Antibody [Clone ID: OTI1H8]

CAT#: TA808513S

EXOSC1 mouse monoclonal antibody, clone OTI1H8 (formerly 1H8)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EXOSC1 (RC206007, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EXOSC1 (1:2000). Positive lysates LY414227 (100ug) and LC414227 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1H8
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human EXOSC1 (NP_057130) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21.3 kDa
• Gene Name: exosome component 1
• Database Link:
  NP_057130
  Entrez Gene 51013 Human
  UniProt ID Q9Y3B2
• Background: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq, Jul 2008]
• Synonyms: CGI-108; CSL4; Csl4p; hCsl4p; p13; SKI4; Ski4p

Reference Data

• Protein Pathways: RNA degradation