PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: OTI1A11]

CAT#: TA807656

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PDGFRA mouse monoclonal antibody, clone OTI1A11 (formerly 1A11)


 Product Datasheet for 'TA807656'

  View other "OTI1A11" antibodies (2)

USD 379.00


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In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI1A11
Applications WB
Recommend Dilution WB 1:200~2000
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 789-1089 of human PDGFRA(NP_006197) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Gene Name platelet derived growth factor receptor alpha
Background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Synonyms CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton

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