PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: OTI1A11]
PDGFRA mouse monoclonal antibody, clone OTI1A11 (formerly 1A11)
Product Datasheet for 'TA807656'
|Recommend Dilution||WB 1:200~2000|
|Immunogen||Human recombinant protein fragment corresponding to amino acids 789-1089 of human PDGFRA(NP_006197) produced in E.coli.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Gene Name||platelet derived growth factor receptor alpha|
|Background||This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]|
|Synonyms||CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane|
|Protein Pathways||Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.